Ræder group
The aim of the research is to better understand mechanisms underlying endocrine disorders in order to optimize personalized diagnosing and treatment (regenerative medicine) of these diseases.
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Group leader: Helge Ræder
To achieve our goals we study patient registries and patient-derived stem cells, directing the cells to become model systems for endocrine disorders, for example diabetes or diseases affecting reproductive cells (ovarian cells and testicular cells), adrenal gland cells and other cell types involved in endocrine systems. By doing so, we are able to better understand both the normal development and the mechanisms behind disease progression.
We employ registry studies, cell biology techniques (immunofluorescence), proteomics, transcription analyses (mRNA), genomics and epigenomics, including miRNA profiling, both for individual cells and tissues, in addition to bioinformatics.
Thus far, we have established and published results from studies in human cell models for diabetes based on skin cells from diabetes patients (MODY patients), and we are trying to develop methods for patients with monogenic causes for disorders of sexual development. The research leader also coordinates a multiregional treatment service for patients with disorders of sexual development. We cooperate with researchers in the US and Switzerland.
Read more at our web page here.
