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Broegelmann Research Laboratory

Broegelmann Research Laboratory

The researchers at the Broegelmann Research Laboratory have a common interest in translational research on chronic inflammatory and autoimmune diseases. The research performed spans from molecular and genetic studies, cellular studies and experimental models as well as studies on clinically well-characterized patient samples. The mutual ambition is to understand the molecular mechanisms active in different inflammatory diseases and their subgroups, their underlying risk factors and triggers. This paves the way for better, personalized treatment and ultimately to prevention of disease.

Main content

Current major areas of research:

  • Translational studies in autoimmunity; autoantibodies and biomarkers
  • Immunopathogenesis of juvenile idiopathic arthritis
  • Functional genomics and genetic basis of the autoimmune exocrinopathy (Sjögren’s disease)
  • Host microbe interactions (P. gingivalis – arthritis, Alzheimer)
  • Hyperinflammatory primary immunodeficiency syndromes
  • Role of HMGB1 in inflammation
  • Novel natural product based COVID-19 therapy
  • Intestinal mucosal microenvironment in irritable bowel syndrome
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