Tools for ETEC vaccine development
Enterotoxigenic Escherichia coli (ETEC) are one of the most important causes of diarrhea in young children in low and middle-income countries (LMIC) as well as in travelers to these countries. Our research focuses on tools for development of an ST-based vaccine candidate and understanding human immune responses against ETEC. More information on the project can be found by following this link.
Low-cost point-of care cryptosporidiosis test in children in Ethiopia (CRYPTO-POC)
The primary objective of this study is to estimate the accuracy and operational performance of simple microscopy of auramine stained stool samples for diagnosis of Cryptosporidium infection. More information on the project can be found by following this link.
Impact of a cryptosporidiosis point-of-care test-and-treat strategy in children with diarrhoea (CryptoT&T)
The CryptoT&T project will assess the clinical effectiveness of LED-microscopy of Auramine Phenol stained fecal smear (LED-AP) testing, in conjunction with access to targeted drug treatment, in reducing the duration of cryptosporidiosis-induced diarrhea. It will evaluate diagnostic accuracy, operational issues, cost-effectiveness, and test turnaround times in a realistic setting in two Sub-Saharan African (SSA) countries. Additionally, it will investigate whether rectal swab samples can expedite test turnaround times compared to bulk stool samples, while maintaining high diagnostic accuracy. Read more about the CryptoT&T-project here.
