Ivar Hordviks forskning fokuserer på komponenter i det adaptive immunsystemet hos fisk. Et langsiktig mål er å utvide spekteret av karakteriserte molekyler og utvikle verktøy som kan brukes til å studere immunresponser i eksperimenter med vaksiner og sykdomsfremkallende organismer hos fisk.

Etter at fisk dannet en egen gren på det fylogenetiske tre har det oppstått betydelige forskjeller mellom fisk og pattedyr, både med hensyn til primærsekvenser av korresponderende molekyler, og ved introduksjon av nye molekyler ved genduplikasjoner. Et eksempel på dette er evolusjonen av immunoglobulinene: Mens IgM har vært evolusjonsmessig stabil og beholdt sin opprinnelige form har IgD vært relativt labil, noe som har resultert i mange ulike IgD-strukturer i forskjellige arter. En nylig oppdaget immunoglobulintype, kalt IgT/IgZ, synes å forekomme kun hos fisk. På den andre siden finnes IgG, IgE og IgA hos pattedyr, men ikke hos fisk.

Mange oppdagelser de siste årene har vist at studier av immunsystemet hos fisk fremdeles kan by på overraskelser. Det er nærliggende å tro at økt kunnskap om immunrelaterte molekyler hos fisk vil få betydning for design av vaksineeksperimenter og tolkning av resultater. Utvikling av nye reagenser til identifisering av immunceller og måling av immunresponser er noe som etterspørres av vaksinefirmaer så vel som av mange forskere.  

Vitenskapelig artikkel

• Etayo, Angela; Bjørgen, Håvard; Koppang, Erling Olaf et al. (2024). The ontogeny of lymphoid organs and IgM⁺ B-cells in ballan wrasse (Labrus bergylta) reveals a potential site for extrarenal B-cell lymphopoiesis: The pancreas. (ekstern lenke)
• Etayo, Angela; Bjørgen, Håvard; Hordvik, Ivar et al. (2024). Possible transport routes of IgM to the gut of teleost fish. (ekstern lenke)
• Bjørgen, Håvard; Barac, Fran; Fjelldal, Per Gunnar et al. (2024). Organisation of the Atlantic salmon (Salmo salar) thymus and its content of Ig-expressing cells. (ekstern lenke)
• Etayo, Angela; Lie, Kai Kristoffer; Bjelland, Reidun Marie et al. (2023). The thymus and T-cell ontogeny in ballan wrasse (Labrus bergylta) is nutritionally modelled. (ekstern lenke)
• Castro, Pedro Luis; Barac, Fran; Hansen, Tom Johnny et al. (2023). The Distribution of IgT mRNA⁺ Cells in the Gut of the Atlantic Salmon (Salmo salar L.). (ekstern lenke)
• Etayo, Angela; Bjørgen, Håvard; Koppang, Erling Olaf et al. (2022). The teleost polymeric Ig receptor counterpart in ballan wrasse (Labrus bergylta) differs from pIgR in higher vertebrates. (ekstern lenke)
• Bilal, Sumaira; Lie, Kai Kristoffer; Dalum, Alf Seljenes et al. (2019). Analysis of immunoglobulin and T cell receptor gene expression in ballan wrasse (Labrus bergylta) revealed an extraordinarily high IgM expression in the gut. (ekstern lenke)
• Løken, Oskar Mongstad; Bjørgen, Håvard; Hordvik, Ivar et al. (2019). A teleost structural analogue to the avian bursa of Fabricius. (ekstern lenke)
• Erkinharju, Toni; Strandskog, Guro; Vågnes, Øyvind et al. (2019). Intramuscular vaccination of Atlantic lumpfish (Cyclopterus lumpus L.) induces inflammatory reactions and local immunoglobulin M production at the vaccine administration site. (ekstern lenke)
• Bjørgen, Håvard; Koppang, Erling Olaf; Gunnes, Gjermund et al. (2018). Ectopic epithelial cell clusters in salmonid intestine are associated with inflammation. (ekstern lenke)
• Bilal, Sumaira; Lie, Kai Kristoffer; Sæle, Øystein et al. (2018). T cell receptor alpha chain genes in the teleost Ballan wrasse (Labrus bergylta) are subjected to somatic hypermutation. (ekstern lenke)
• Aas, Ida Bergva; Austbø, Lars; Falk, Knut et al. (2017). The interbranchial lymphoid tissue likely contributes to immune tolerance and defense in the gills of Atlantic salmon. (ekstern lenke)
• Erkinharju, Toni; Dalmo, Roy Ambli; Vågsnes, Øyvind et al. (2017). Vaccination of Atlantic lumpfish (Cyclopterus lumpus L.) at a low temperature leads to a low antibody response against Aeromonas salmonicida. (ekstern lenke)
• Erkinharju, Toni; Lundberg, Martin, Rønbeck; Isdal, Eivind et al. (2017). Studies on the antibody response and side effects after intramuscular and intraperitoneal injection of Atlantic lumpfish (Cyclopterus lumpus L.) with different oil-based vaccines. (ekstern lenke)
• Dalum, Alf Seljenes; Tangen, Randi; Falk, Knut et al. (2016). Coronary changes in the Atlantic salmon Salmo salar L: characterization and impact of dietary fatty acid compositions. (ekstern lenke)
• Bilal, Sumaira; Lie, Kai Kristoffer; Karlsen, Odd Andre et al. (2016). Characterization of IgM in Norwegian cleaner fish (lumpfish and wrasses). (ekstern lenke)
• Hordvik, Ivar (2015). Immunoglobulin Isotypes in Atlantic Salmon, Salmo Salar. (ekstern lenke)
• Dalum, Alf Seljenes; Austbø, Lars; Bjørgen, Håvard et al. (2015). The interbranchial lymphoid tissue of Atlantic Salmon (Salmo salar L) extends as a diffuse mucosal lymphoid tissue throughout the trailing edge of the gill filament. (ekstern lenke)
• Aas, Ida Bergva; Austbø, Lars; Kønig, Melanie et al. (2014). Transcriptional characterization of the T cell population within the salmonid interbranchial lymphoid tissue. (ekstern lenke)
• Løkka, Guro; Austbø, Lars; Falk, Knut et al. (2014). Immune parameters in the intestine of wild and reared unvaccinated and vaccinated Atlantic salmon (Salmo salar L.). (ekstern lenke)
• Yousaf, Muhammed; Koppang, Erling Olaf; Skjødt, Karsten et al. (2013). Comparative cardiac pathological changes of Atlantic salmon (Salmo salar L.) affected with heart and skeletal muscle inflammation (HSMI), cardiomyopathy syndrome (CMS) and pancreas disease (PD). (ekstern lenke)
• Kamil, Atif; Raae, Arnt Johan; Fjelldal, Per Gunnar et al. (2013). Comparative analysis of IgM sub-variants in salmonid fish and identification of a residue in mu 3 which is essential for MAb4C10 reactivity. (ekstern lenke)
• Yousaf, Muhammed; Koppang, Erling Olaf; Skjødt, Karsten et al. (2012). Cardiac pathological changes of Atlantic salmon (Salmo salar L.) affected with heart and skeletal muscle inflammation (HSMI). (ekstern lenke)
• Larsen, Hilde; Austbø, Lars; Mørkøre, Turid et al. (2012). Pigment-producing granulomatous myopathy in Atlantic salmon: A novel inflammatory response. (ekstern lenke)
• Wiik-Nielsen, Jannicke; Løvoll, Marie Therese; Fritsvold, Camilla et al. (2012). Characterization of myocardial lesions associated with cardiomyopathy syndrome in Atlantic salmon, Salmo salar L., using laser capture microdissection. (ekstern lenke)
• Tadiso, Tariku Markos; Lie, Kai Kristoffer; Hordvik, Ivar (2011). Molecular cloning of IgT from Atlantic salmon, and analysis of the relative expression of tau, mu, and delta in different tissues. (ekstern lenke)
• Tadiso, Tariku Markos; Sharma, Animesh; Hordvik, Ivar (2011). Analysis of polymeric immunoglobulin receptor- and CD300-like molecules from Atlantic salmon. (ekstern lenke)
• Tadiso, Tariku Markos; Krasnov, Aleksei; Skugor, Stanko et al. (2011). Gene expression analyses of immune responses in Atlantic salmon during early stages of infection by salmon louse (Lepeophtheirus salmonis) revealed bi-phasic responses coinciding with the copepod-chalimus transition. (ekstern lenke)
• Kamil, Atif; Falk, Knut; Sharma, Animesh et al. (2011). A monoclonal antibody distinguishes between two IgM heavy chain isotypes in Atlantic salmon and brown trout: Protein characterization, 3D modeling and epitope mapping. (ekstern lenke)
• Koppang, Erling Olaf; Fischer, Uwe; Moore, Lindsey et al. (2010). Salmonid T cells assemble in the thymus, spleen and in novel interbranchial lymphoid tissue. (ekstern lenke)
• Moore, Lindsey; Dijkstra, J.M; Koppang, Erling Olaf et al. (2009). CD4 homologues in Atlantic salmon. (ekstern lenke)
• Moore, Lindsey; Dijkstra, Johannes Martinus ; Koppang, Erling Olaf et al. (2009). CD4 homologues in Atlantic salmon. (ekstern lenke)
• Øvergård, Aina-Cathrine; Hordvik, Ivar; Nerland, Audun H. et al. (2009). Cloning and expression analysis of Atlantic halibut (Hippoglossus hippoglossus) CD3 genes. (ekstern lenke)
• Haugarvoll, Erlend; Bjerkås, Inge; Nowak, BF et al. (2008). Identification and characterization of a novel intraepithelial lymphoid tissue in the gills of Atlantic salmon. (ekstern lenke)
• Liu, Yun; Moore, Lindsey; Koppang, Erling Olaf et al. (2008). Characterization of the CD3f, CD3cd and CD3e subunits of the T cell receptor complex in Atlantic salmon. (ekstern lenke)
• Haugarvoll, Erlend; Bjerkås, Inge; Nowak, Barbara F. et al. (2008). Identification and characterization of a novel intraepithelial lymphoid tissue in the gills of Atlantic salmon. (ekstern lenke)
• Liu, Yun; Moore, Lindsey; Koppang, Erling Olaf et al. (2008). Characterization of the CD3 zeta, CD3 gamma delta and CD3 epsilon subunits of the T cell receptor complex in Atlantic salmon. (ekstern lenke)
• Morrison, RN; Koppang, Erling Olaf; Hordvik, Ivar et al. (2006). MHC class ll+ cells in the gills of Atlantic salmon ( Salmo salar L.) affected by amoebic gill disease. (ekstern lenke)
• Morrison, Richard N.; Koppang, Erling Olaf; Hordvik, Ivar et al. (2006). MHC class II+ cells in the gills of Atlantic salmon (Salmo salar L.) affected by amoebic gill disease. (ekstern lenke)
• Hevrøy, Ernst Morten; Jordal, Ann-Elise Olderbakk; Hordvik, Ivar et al. (2006). Myosin heavy chain mRNA expression correlates higher with muscle protein accretion than growth in Atlantic salmon, Salmo salar. (ekstern lenke)
• Dijkstra, Johannes Martinus ; Somamoto, Tomonori; Moore, Lindsey et al. (2006). Identification and characterization of a second CD4-like gene in teleost fish. (ekstern lenke)
• Fischer, Uwe; Dijkstra, J.M; Kollner, B et al. (2005). The ontogeny of MHC class I expression in rainbow trout (Oncorhynchus mykiss). (ekstern lenke)
• Koppang, Erling Olaf; Haugarvoll, Erlend; Hordvik, Ivar et al. (2005). Vaccine-associated granulomatous inflammation and melanin accumulation in Atlantic salmon, Salmo salar L., white muscle. (ekstern lenke)
• Olsvik, Pål A.; Lie, Kai Kristoffer; Olderbakk Jordal, Anne-Lise et al. (2005). Evaluation of potential reference genes in real-time RT-PCR studies of Atlantic salmon. (ekstern lenke)
• Van Do, Thien; Elsayed, Said; Florvaag, Erik et al. (2005). Allergy to fish parvalbumins: Studies on the cross-reactivity of allergens from 9 commonly consumed fish. (ekstern lenke)
• Koppang, Erling Olaf; Haugarvoll, E; Hordvik, Ivar et al. (2005). Vaccine-associated granulomatous inflammation and melanin accumulation in Atlantic salmon, Salmo salar L., white muscle. (ekstern lenke)
• Van Do, Thien; Hordvik, Ivar; Endresen, Curt et al. (2005). Characterization of parvalbumin, the major allergen in Alaska pollack, and comparison with codfish Allergen M. (ekstern lenke)
• Moore, LJ; Somamoto, T; Lie, KK et al. (2005). Characterisation of salmon and trout CD8 alpha and CD8 beta. (ekstern lenke)
• Fischer, Uwe; Dijkstra, Johannes Martinus ; Köllner, Bernd et al. (2005). The ontogeny of MHC class I expression in rainbow trout (Oncorhynchus mykiss). (ekstern lenke)
• Koppang, Erling Olaf; Haugarvoll, Erlend; Hordvik, Ivar et al. (2004). Granulomatous uveitis associated with vaccination in the Atlantic salmon. (ekstern lenke)
• Hordvik, Ivar; Torvund, Jannicke; Moore, Lindsey et al. (2004). Structure and organization of the T cell receptor alpha chain genes in Atlantic salmon. (ekstern lenke)
• Koppang, Erling Olaf; Haugarvoll, E; Hordvik, Ivar et al. (2004). Granulomatous uveitis associated with vaccination in the Atlantic salmon. (ekstern lenke)
• Koppang, Erling Olaf; Hordvik, Ivar; Bjerkås, Inge et al. (2003). Production of rabbit antisera against recombinant MHC class II B chain and identification of immunoreactive cells in Atlantic salmon (Salmo salar). (ekstern lenke)
• Koppang, Erling Olaf; Bjerkås, Ellen; Bjerkås, Inge et al. (2003). Vaccination induces major histocompatibility complex class II expression in the Atlantic salmon eye. (ekstern lenke)
• Koppang, Erling Olaf; Bjerkås, Ellen; Bjerkås, Inge et al. (2003). Vaccination Induces Major Histocompatibility Complex Class II Expression in the Atlantic Salmon Eye. (ekstern lenke)
• Koppang, Erling Olaf; Hordvik, Ivar; Bjerkås, Inge et al. (2003). Production of rabbit antisera against recombinant MHC class II beta chain and identification of immunoreactive cells in Atlantic salmon (Salmo salar). (ekstern lenke)
• Hordvik, Ivar; Koppang, Erling Olaf (2002). Karakterisering av immungener hos fisk. Litt historikk, status og fremtidsutsikter. (ekstern lenke)
• Hordvik, Ivar (2002). Identification of a novel immunoglobulin δ transcript and comparative analysis of the genes encoding IgD in Atlantic salmon and Atlantic halibut. (ekstern lenke)
• Hordvik, Ivar; Berven, Frode; Solem, Stein Tore et al. (2002). Analysis of two IgM isotypes in Atlantic salmon and brown trout. (ekstern lenke)
• Solem, Stein T.; Hordvik, Ivar; Killie, Jan-Eirik A. et al. (2001). Diversity of the immunoglobulin heavy chain in the Atlantic salmon (Salmo salar L.) is contributed by genes from two parallel IgH isoloci. (ekstern lenke)
• Hatten, Frode; Fredriksen, Åse; Hordvik, Ivar et al. (2001). Presence of IgM in cutaneous mucus, but not in gut mucus of Atlantic salmon, Salmo salar. Serum IgM is rapidly degraded when added to gut mucus. (ekstern lenke)
• Do, Thien van; Hordvik, Ivar; Endresen, Curt et al. (1999). Expression and analysis of recombinant salmon parvalbumin, the major allergen in Atlantic salmon (Salmo salar). (ekstern lenke)
• Krossøy, Bjørn; Hordvik, Ivar; Nilsen, Frank et al. (1999). The putative polymerase sequence of infectious salmon anemia virus suggests a new genus within the Orthomyxoviridae. (ekstern lenke)
• Hordvik, Ivar; Thevarajan, J.; Samdal, I. et al. (1999). Molecular cloning and phylogenetic analysis of the Atlantic salmon Immunoglobulin D gene. (ekstern lenke)
• Van Do, Thien; Hordvik, Ivar; Endresen, Curt et al. (1999). Expression and analysis of recombinant salmon parvalbumin, the major allergen in Atlantic salmon (Salmo salar). (ekstern lenke)
• Nilsen, Frank; Endresen, Curt; Hordvik, Ivar (1998). Molecular phylogeny of mcrosoridians with particular reference to species that infect the muscles of fish. (ekstern lenke)
• Hordvik, Ivar (1998). The impact of ancestral tetraploidy on antibody heterogeneity in salmonid fishes. (ekstern lenke)
• Hordvik, Ivar; Lindstrøm, Christian De Vries; Voie, Ann-Mari et al. (1997). Structure and organization of the immunoglobulin M heavy chain genes in Atlantic salmon, Salmo salar. (ekstern lenke)
• Elsayed, Said; Lindstrøm, c.d-v; Van Do, Thien et al. (1996). Cloning of two distinct cDNA encoding parvalbumin, the major allergen of Atlantic salmon (Salmo salar). (ekstern lenke)
• Hordvik, Ivar; Jacob, Anne Lilybert J.; Charlemagne, Jacques et al. (1996). Cloning of T-cell antigen receptor beta chain cDNAs from Atlantic salmon (Salmo salar). (ekstern lenke)
• Nylund, Are; Hordvik, Ivar; Endresen, Curt (1996). Avl og sykdomsresistens. (ekstern lenke)
• Lindstrøm, Christian De Vries; Van Do, Thien; Hordvik, Ivar et al. (1996). Cloning of two distinct cDNAs encoding parvalbumin, the major allergen of Atlantic salmon (Salmo salar). (ekstern lenke)
• Lie, Ø.; Slettan, A.; Lingaas, F. et al. (1994). Haploid gynogenesis. A powerful strategy for linkage analysis in fish. (ekstern lenke)
• Hordvik, Ivar (1994). Immune genes of the Atlantic salmon. Application of modern genetic techniques to the study of antibodies and MHC antigens from Atlantic salmon. (ekstern lenke)
• Grimholt, U.; Hordvik, Ivar; Fosse, Vivian Jacobsen et al. (1993). Molecular cloning of major histocompability complex class I cDNAs from Atlantic salmon (Salmo salar). (ekstern lenke)
• Hordvik, Ivar; Grimholt, Unni; Fosse, Viggo M. et al. (1993). Cloning and sequence analysis of cDNAs encoding the MHC class II beta chain in Atlantic salmon (Salmo salar). (ekstern lenke)
• Molven, Anders; Hordvik, Ivar; Njølstad, Pål Rasmus et al. (1992). The zebrafish homeobox gene Hox(zf-114): primary structure, expression pattern and evolutionary aspects. (ekstern lenke)
• Hordvik, Ivar; Voie, A. M.; Glette, J. et al. (1992). Cloning and sequence analysis of two isotopic IgM heavy chain genes from Atlantic salmon, Salmo salar L. (ekstern lenke)

Vitenskapelig oversiktsartikkel/review

• Bilal, Sumaira; Etayo, Angela; Hordvik, Ivar (2021). Immunoglobulins in teleosts. (ekstern lenke)

Poster

• Bjørgen, Håvard; Hordvik, Ivar; Koppang, Erling Olaf (2019). Inflammatory changes and melanization in the Atlantic salmon (Salmo salar) targeted by in situ hybridization. (ekstern lenke)
• Erkinharju, Toni; Strandskog, Guro; Vågnes, Øyvind Brune et al. (2019). Intramuscular injection of an oil-based vaccine in Atlantic lumpfish induces local IgM production.. (ekstern lenke)
• Moldal, Torfinn; Koppang, Erling Olaf; Kaldhusdal, Magne et al. (2011). Intestinal epithelial dysplasia and adenocarcinoma in salmonids is associated with inflammation. (ekstern lenke)
• Yousaf, Muhammad Naveed; Powell, Mark; Koppang, Erling Olaf et al. (2011). Comparative pathology of cardiac diseases in Atlantic salmon (Salmo salar L.) by immunohistochemistry.. (ekstern lenke)
• Yousaf, Muhammed; Powell, Mark Darryn; Koppang, Erling Olaf et al. (2010). Comparative pathology of cardiac diseases in Atlantic salmon (Salmo salar L.) by immunohistochemistry. (ekstern lenke)
• Bakke McKellep, Anne Marie; Koppang, Erling Olaf; Hordvik, Ivar et al. (2003). Major histocompatibility complex (MHC) class II expression during soybean meal-induced enteritis in Atlantic salmon (Salmo salar L.). (ekstern lenke)
• Bakke McKellep, Anne Marie; Koppang, Erling Olaf; Hordvik, Ivar et al. (2003). Major histocompatibility complex (MHC) class II expression during soybean meal-induced enteritis in Atlantic salmon (Salmo salar L.). (ekstern lenke)
• Hordvik, Ivar (2002). The immunoglobulin heavy chain gene loci in Atlantic salmon: Analysis of IgM subvariants related to ancestral tetraploidy and identification of a novel IgD transcript. (ekstern lenke)
• Hordvik, Ivar (2002). Analyse av immunoglobulin D uttrykking hos laks. (ekstern lenke)

Doktorgradsavhandling

• Bilal, Sumaira; Hordvik, Ivar; Karlsen, Odd Andre (2019). Molecular characterization of key components of the adaptive immune system in ballan wrasse (Labrus bergylta). (ekstern lenke)
• Hordvik, Ivar (1993). Immune genes of the Atlantic salmon. Cloning and sequence analyses of genes encoding the IgM heavy chain, the MHC class I alpha-chain and the MHC class II beta-chain. (ekstern lenke)

Vitenskapelig foredrag

• Løken, Oskar Mongstad; Bjørgen, Håvard; Hordvik, Ivar et al. (2019). Distribution of different populations of T cells and B cells in the interbranchial lymphoid tissue (ILT) of salmon. (ekstern lenke)
• Bjørgen, Håvard; Haldorsen, Randi; Oaland, Øyvind et al. (2019). Characterization and development of focal red and melanised changes in the Atlantic salmon. (ekstern lenke)
• Erkinharju, Toni; Strandskog, Guro; Vågnes, Øyvind Brune et al. (2019). Intramuscular vaccination of Atlantic lumpfish induces inflammation and local IgM production.. (ekstern lenke)
• Erkinharju, Toni; Lundberg, Martin Rønbeck; Isdal, Eivind et al. (2017). Intramuscular injection of oil-based vaccines in Atlantic lumpfish (Cyclopterus lumpus L.) – a possible route of administration or not? Emphasis on fish welfare and immune response . (ekstern lenke)
• Erkinharju, Toni; Lundberg, Martin, Rønbeck; Isdal, Eivind et al. (2017). Intramuscular injection of oil-based vaccines in Atlantic lumpfish (Cyclopterus lumpus L.) – a possible route of administration or not?. (ekstern lenke)
• Koppang, Erling Olaf; Kaldhusdal, Magne; Hordvik, Ivar et al. (2011). Tarmkreft hos laksefisk er assosiert med betennelse. (ekstern lenke)
• Hordvik, Ivar; Lie, Kai K; Koppang, Erling Olaf (2003). Analysis of IgD expression in Atlantic salmon. (ekstern lenke)
• Koppang, Erling Olaf; Hordvik, Ivar; Bjerkås, Inge (2002). Detection of MHC class II positive cells in the Atlantic salmon (Salmo salar). (ekstern lenke)
• Koppang, Erling Olaf; Hordvik, Ivar; Bjerkås, Inge (2002). Detection of MHC class II positive cells in the Atlantic salmon (Salmo salar). (ekstern lenke)
• Hordvik, Ivar (2001). Identification of IgD heavy chain RNA splice variants in Atlantic salmon, Salmo salar. (ekstern lenke)
• Hordvik, Ivar (2001). Analyse av immunoglobulin D uttrykking hos laks. (ekstern lenke)
• Hordvik, Ivar; Hatten, Frode; Solem, Stein Tore et al. (2000). IgM and IgD heavy chain subvariants in Atlantic salmon and brown trout, related to ancestral tetraploidy. (ekstern lenke)
• Grimholt, Unni; Hordvik, Ivar; Olsaker, Ingrid et al. (1993). MHC polymorphism in Atlantic salmon. (ekstern lenke)
• Hordvik, Ivar; Voie, Ann Mari; Lindstrøm, Christian De Vries et al. (1993). Two isotypic IgM heavy chain genes of the Atlantic salmon. (ekstern lenke)

Populærvitenskapelig artikkel

• Hordvik, Ivar (2014). Laksen har dobbelt sett med gener (INNSIKT-artikkel). (ekstern lenke)
• Hordvik, Ivar (1999). En nyoppdaget type antistoffer hos beinfisk. (ekstern lenke)

Sammendrag/abstract

• Løkka, Guro; Austbø, Lars; Falk, Knut et al. (2013). Expression of immune related genes in the Atlantic salmon intestine. (ekstern lenke)
• Aas, Ida Bergva; Austbø, Lars; Kønig, Melanie et al. (2013). The immunological function of the interbranchial lymphoid tissue (ILT). (ekstern lenke)
• Hordvik, Ivar; Kamil, Atif; Bilal, Sumaira et al. (2013). Characterization of serum IgM in teleost fish, with emphasis on salmonids. (ekstern lenke)
• Frøyse, Alf Lars Dalum; Thorsen, Jim; Austbø, Lars et al. (2013). Anatomy of the interbranchial lymphoid tissue (ILT) in salmonid fish. (ekstern lenke)

Fagartikkel

• Kamil, Atif; Fjelldal, Per Gunnar; Hansen, Tom Johnny et al. (2013). VACCINATION of Atlantic salmon leads to long-lasting higher levels of serum immunoglobulin and possible skewed ratios of two distinct IgM isotypes. (ekstern lenke)

Leserinnlegg

• Hordvik, Ivar; Mortensen, Stein (2011). Ville reinsdyr trives best. (ekstern lenke)

Hovedfagsoppgave

• Espedal, Per Gunnar; Pittman, Karin; Hordvik, Ivar (2007). Deteksjon av IgM-positive celler i blodutstryk fra kveite (Hippoglossus hippoglossus L.): in situ hybridisering med to typer prober. (ekstern lenke)
• Samdal, Ingvild; Hordvik, Ivar; Szilvay, Anne Marie (2004). Expression of two fragments from the atlantic salmon major histocompability class 1α chain in E.coli, utilizing two different. (ekstern lenke)
• Lie, Kai Kristoffer; Hordvik, Ivar (2004). Analyse av IgM- og IgD-genuttrykking i ulike vev hos atlantisk laks (Salmo salar L.). (ekstern lenke)

Vitenskapelig Kapittel/Artikkel/Konferanseartikkel

• Robertsen, Børre; Hordvik, Ivar; Jørgensen, Trond Ø. (2007). The fish immune system. (ekstern lenke)
• Robertsen, Børre; Hordvik, Ivar; Jørgensen, Trond Ø (2006). Immunsystemet hos fisk. (ekstern lenke)

Kronikk

• Van Do, Thien; Hordvik, Ivar; Endresen, Curt et al. (1997). cDNA cloning and expression of two parvalbumins, the major allergens of Atlantic salmon (Salmo salar). (ekstern lenke)
• Van, Dô; Hordvik, Ivar; Endresen, Curt et al. (1997). cDNA cloning and expression of two parvalbumins, the major allergens of Atlantic salmon (Salmo salar). (ekstern lenke)

Se en full oversikt over publikasjoner i Cristin

 

Cloning and expression analysis of Atlantic halibut (Hippoglossus hippoglossus) CD3 genes
Author(s): Overgard, AC; Hordvik, I; Nerland, AH, et al.
Source: FISH & SHELLFISH IMMUNOLOGY   Volume: 27   Issue: 6   Pages: 707-713   Published: 2009

 

CD4 homologues in Atlantic salmon
Author(s): Moore, LJ; Dijkstra, JM; Koppang, EO, et al.
Source: FISH & SHELLFISH IMMUNOLOGY   Volume: 26   Issue: 1   Pages: 10-18   Published: 2009

 

Identification and characterization of a novel intraepithelial lymphoid tissue in the gills of Atlantic salmon
Author(s): Haugarvoll, E; Bjerkas, I; Nowak, BF, et al.
Source: JOURNAL OF ANATOMY   Volume: 213   Issue: 2   Pages: 202-209   Published: 2008

 

Characterization of the CD3 zeta, CD3 gamma delta and CD3 epsilon subunits of the T cell receptor complex in Atlantic salmon
Author(s): Liu, Y; Moore, L; Koppang, EO, et al.
Source: DEVELOPMENTAL AND COMPARATIVE IMMUNOLOGY   Volume: 32   Issue: 1   Pages: 26-35   Published: 2008

 

FABP3 and FABP10 in Atlantic salmon (Salmo salar L.) - General effects of dietary fatty acid composition and life cycle variations
Author(s): Jordal, AEO; Hordvik, I; Pelsers, M, et al.
Source: COMPARATIVE BIOCHEMISTRY AND PHYSIOLOGY B-BIOCHEMISTRY & MOLECULAR BIOLOGY   Volume: 145   Issue: 2   Pages: 147-158   Published: OCT 2006

 

Myosin heavy chain mRNA expression correlates higher with muscle protein accretion than growth in Atlantic salmon, Salmo salar
Author(s): Hevroy, EM; Jordal, AEO; Hordvik, I, et al.
Source: AQUACULTURE   Volume: 252   Issue: 2-4   Pages: 453-461   Published: MAR 10 2006

 

Identification and characterization of a second CD4-like gene in teleost fish
Author(s): Dijkstra, JM; Somamoto, T; Moore, L, et al.
Source: MOLECULAR IMMUNOLOGY   Volume: 43   Issue: 5   Pages: 410-419   Published: FEB 2006

 

MHC class II+ cells in the gills of Atlantic salmon (Salmo salar L.) affected by amoebic gill disease
Author(s): Morrison, RN; Koppang, EO; Hordvik, I, et al.
Source: VETERINARY IMMUNOLOGY AND IMMUNOPATHOLOGY   Volume: 109   Issue: 3-4   Pages: 297-303   Published: FEB 15 2006

 

Allergy to fish parvalbumins: Studies on the cross-reactivity of allergens from 9 commonly consumed fish
Author(s): Van Do, T; Elsayed, S; Florvaag, E, et al.
Source: JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY   Volume: 116   Issue: 6   Pages: 1314-1320   Published: DEC 2005

 

Evaluation of potential reference genes in real-time RT-PCR studies of Atlantic salmon
Author(s): Olsvik, PA; Lie, KK; Jordal, AEO, et al.
Source: BMC MOLECULAR BIOLOGY   Volume: 6   Article Number: 21   Published: NOV 17 2005

 

Characterisation of salmon and trout CD8 alpha and CD8 beta
Author(s): Moore, LJ; Somamoto, T; Lie, KK, et al.
Source: MOLECULAR IMMUNOLOGY   Volume: 42   Issue: 10   Pages: 1225-1234   Published: JUN 2005

 

Characterization of parvalbumin, the major allergen in Alaska pollack, and comparison with codfish Allergen M
Author(s): Van Do, T; Hordvik, I; Endresen, C, et al.
Source: MOLECULAR IMMUNOLOGY   Volume: 42   Issue: 3   Pages: 345-353   Published: FEB 2005

 

The ontogeny of MHC class I expression in rainbow trout (Oncorhynchus mykiss)
Author(s): Fischer, U; Dijkstra, JM; Kollner, B, et al.
Source: FISH & SHELLFISH IMMUNOLOGY   Volume: 18   Issue: 1   Pages: 49-60   Published: JAN 2005

 

Vaccine-associated granulomatous inflammation and melanin accumulation in Atlantic salmon, Salmo salar L., white muscle
Author(s): Koppang, EO; Haugarvoll, E; Hordvik, I, et al.
Source: JOURNAL OF FISH DISEASES   Volume: 28   Issue: 1   Pages: 13-22   Published: JAN 2005

 

Structure and organization of the T cell receptor alpha chain genes in Atlantic salmon
Author(s): Hordvik, I; Torvund, J; Moore, L, et al.
Source: MOLECULAR IMMUNOLOGY   Volume: 41   Issue: 5   Pages: 553-559   Published: JUL 2004

 

Granulomatous uveitis associated with vaccination in the Atlantic salmon
Author(s): Koppang, EO; Haugarvoll, E; Hordvik, I, et al.
Source: VETERINARY PATHOLOGY   Volume: 41   Issue: 2   Pages: 122-130   Published: MAR 2004

 

Vaccination induces major histocompatibility complex class II expression in the Atlantic salmon eye
Author(s): Koppang, EO; Bjerkas, E; Bjerkas, I, et al.
Source: SCANDINAVIAN JOURNAL OF IMMUNOLOGY   Volume: 58   Issue: 1   Pages: 9-14   Published: JUL 2003

 

The major allergen (parvalbumin) of codfish is encoded by at least two isotypic genes: cDNA cloning, expression and antibody binding of the recombinant allergens
Author(s): Van Do, T; Hordvik, I; Endresen, C, et al.
Source: MOLECULAR IMMUNOLOGY   Volume: 39   Issue: 10   Pages: 595-602   Published: JAN 2003

 

Analysis of two IgM isotypes in Atlantic salmon and brown trout
Author(s): Hordvik, I; Berven, FS; Solem, ST, et al.
Source: MOLECULAR IMMUNOLOGY   Volume: 39   Issue: 5-6   Pages: 313-321   Published: OCT 2002

 

Identification of a novel immunoglobulin delta transcript and comparative analysis of the genes encoding IgD in Atlantic salmon and Atlantic halibut
Author(s): Hordvik, I
Source: MOLECULAR IMMUNOLOGY   Volume: 39   Issue: 1-2   Pages: 85-91   Published: SEP 2002

 

Diversity of the immunoglobulin heavy chain in the Atlantic salmon (Salmo salar L.) is contributed by genes from two parallel IgH isoloci.
Author(s): Solem, ST; Hordvik, I; Killie, JEA, et al.
Source: DEVELOPMENTAL AND COMPARATIVE IMMUNOLOGY   Volume: 25   Issue: 5-6   Pages: 403-417   Published: JUN-JUL 2001

 

Presence of IgM in cutaneous mucus, but not in gut mucus of Atlantic salmon, Salmo salar. Serum IgM is rapidly degraded when added to gut mucus
Author(s): Hatten, F; Fredriksen, A; Hordvik, I, et al.
Source: FISH & SHELLFISH IMMUNOLOGY   Volume: 11   Issue: 3   Pages: 257-268   Published: APR 2001

 

Expression and analysis of recombinant salmon parvalbumin, the major allergen in atlantic salmon (Salmo salar)
Author(s): Van Do, T; Hordvik, I; Endresen, C, et al.
Source: SCANDINAVIAN JOURNAL OF IMMUNOLOGY   Volume: 50   Issue: 6   Pages: 619-625   Published: 1999

 

Molecular cloning and phylogenetic analysis of the Atlantic salmon immunoglobulin D gene
Author(s): Hordvik, I; Thevarajan, J; Samdal, I, et al.
Source: SCANDINAVIAN JOURNAL OF IMMUNOLOGY   Volume: 50   Issue: 2   Pages: 202-210   Published: AUG 1999

 

The putative polymerase sequence of infectious salmon anemia virus suggests a new genus within the Orthomyxoviridae
Author(s): Krossoy, B; Hordvik, I; Nilsen, F, et al.
Source: JOURNAL OF VIROLOGY   Volume: 73   Issue: 3   Pages: 2136-2142   Published: MAR 1999

 

The impact of ancestral tetraploidy on antibody heterogeneity in salmonid fishes
Author(s): Hordvik, I
Source: IMMUNOLOGICAL REVIEWS   Volume: 166   Pages: 153-157   Published: DEC 1998

 

Molecular phylogeny of microsporidians with particular reference to species that infect the muscles of fish
Author(s): Nilsen, F; Endresen, C; Hordvik, I
Source: JOURNAL OF EUKARYOTIC MICROBIOLOGY   Volume: 45   Issue: 5   Pages: 535-543   Published: SEP-OCT 1998

 

Structure and organization of the immunoglobulin M heavy chain genes in Atlantic salmon, Salmo salar
Author(s): Hordvik, I; Lindstrom, CD; Voie, AM, et al.
Source: MOLECULAR IMMUNOLOGY   Volume: 34   Issue: 8-9   Pages: 631-639   Published: JUN 1997

 

Cloning of T-cell antigen receptor beta chain cDNAs from Atlantic salmon (Salmo salar)
Author(s): Hordvik, I; Jacob, ALJ; Charlemagne, J, et al.
Source: IMMUNOGENETICS   Volume: 45   Issue: 1   Pages: 9-14   Published: 1996

 

Cloning of two distinct cDNAs encoding parvalbumin, the major allergen of Atlantic salmon (Salmo salar)
Author(s): Lindstrom, CDV; VanDo, T; Hordvik, I, et al.
Source: SCANDINAVIAN JOURNAL OF IMMUNOLOGY   Volume: 44   Issue: 4   Pages: 335-344   Published: OCT 1996

 

Immune genes of the Atlantic salmon, Salmo salar L.: Application of modern molecular genetic techniques to the study of antibodies and major histocompatibility complex antigens
Author(s): Hordvik, I.
Source: Aquaculture and Fisheries Management   Volume: 25   Issue: 1   Pages: 47-53   Published: 1994

 

Haploid gynogenesis: A powerful strategy for linkage analysis in fish
Author(s): Lie, O.; Slettan, A.; Lingaas, F., et al.
Source: Animal Biotechnology   Volume: 5   Issue: 1   Pages: 33-45   Published: 1994

 

MOLECULAR-CLONING OF MAJOR HISTOCOMPATIBILITY COMPLEX CLASS-I CDNAS FROM ATLANTIC SALMON (SALMO-SALAR)
Author(s): GRIMHOLT, U; HORDVIK, I; FOSSE, VM, et al.
Source: IMMUNOGENETICS   Volume: 37   Issue: 6   Pages: 469-473   Published: FEB 1993

 

CLONING AND SEQUENCE-ANALYSIS OF CDNAS ENCODING THE MHC CLASS-II BETA-CHAIN IN ATLANTIC SALMON (SALMO-SALAR)
Author(s): HORDVIK, I; GRIMHOLT, U; FOSSE, VM, et al.
Source: IMMUNOGENETICS   Volume: 37   Issue: 6   Pages: 437-441   Published: FEB 1993

 

CLONING AND SEQUENCE-ANALYSIS OF 2 ISOTYPIC IGM HEAVY-CHAIN GENES FROM ATLANTIC SALMON, SALMO-SALAR L
Author(s): HORDVIK, I; VOIE, AM; GLETTE, J, et al.
Source: EUROPEAN JOURNAL OF IMMUNOLOGY   Volume: 22   Issue: 11   Pages: 2957-2962   Published: NOV 1992