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Centre for Deep Sea Research

Diversity of biosynthetic gene clusters and antimicrobial peptides in Arctic deep-sea hydrothermal vent microbiomes

PhD project of Trong Thuc Nguyen

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PhD project

Diversity of biosynthetic gene clusters and antimicrobial peptides in Arctic deep-sea hydrothermal vent microbiomes

Supervisors

Runar Stokke and Ida Helene Steen

Project description

Trong Thuc Nguyen is a Ph.D. Research Fellow in the NRC-funded DeepSeaQuence project at the Department of Biological Sciences, University of Bergen.

His Ph.D. research project focuses on the diversity of microbial communities at Arctic deep-sea hydrothermal vents and their potential biological products. The project will explore the metagenomics and metatranscriptomics data from the deep-sea microbiota to investigate the diversity of biosynthetic gene clusters (BGCs) and novel anti-microbial peptides (AMPs) among those microbial genomes. With -omic technologies, the goal is to investigate those metabolic interactions inside the deep-sea microbial communities and search for novel biological compounds that can be applied in biotechnology, and to infer potential ecological roles of such compounds.