- E-mailsalwa.suliman@uib.no
- Phone+47 55 58 63 56
- Visitor AddressÅrstadveien 195009 Bergen
- Postal AddressPostboks 78045020 Bergen
I hold a Bachelor’s in Dentistry from University of Khartoum, Sudan and a Ph.D. in Tissue Engineering from the University of Bergen, where I was awarded Faculty of Medicine’s best PhD prize. I investigated the efficacy and immune responses of functionalised bioactive scaffolds in delivering growth factors for bone tissue engineering. I continued as a post doctor in the Tissue Engineering group at UiB with a research fellowship at Department of Applied Oral Sciences at The Forsyth Institute and Harvard School of Dental Medicine, USA. My research efforts were recognised by the Meltzer Prize for Outstanding Young Researchers in 2020.
Currently, my research is centred on immune-driven tissue regeneration. My overarching goal is to create conducive environments for the regeneration of injured tissues, with a specific focus on understanding and harnessing the impact of the immune system on regeneration, particularly in the realm of stem-cell based bone regeneration. Employing a combination of in vitro and in vivo translational methodologies, we strive to unravel insights into the intricate crosstalk between immune cells and stem cells within the context of regenerative engineering. Additionally, we aim to use this knowledge to promote regeneration in compromised healing and to design regenerative biomaterials with osteoimmunomodulatory properties.
What Happens in a Bone Tissue Engineering Lab? - YouTube - A tour briefly showing how we use stem cells to engineer bone in a research lab at the University of Bergen - Department of Clinical Dentistry - (Tissue Engineering Research Group). The content of the video is created with the aim of targeting high school students and the general public audience.
- (2023). Xeno-free generation of human induced pluripotent stem cells from donor-matched fibroblasts isolated from dermal and oral tissues. Stem Cell Research & Therapy.
- (2023). Embryonic Stem Cells Can Generate Oral Epithelia under Matrix Instruction. International Journal of Molecular Sciences. 13 pages.
- (2022). Influence of Bone Substitutes on Mesenchymal Stromal Cells in an Inflammatory Microenvironment. International Journal of Molecular Sciences. 15 pages.
- (2022). Immune-instructive copolymer scaffolds using plant-derived nanoparticles to promote bone regeneration. Inflammation and Regeneration.
- (2022). Extracellular Vesicles Derived from Primed Mesenchymal Stromal Cells Loaded on Biphasic Calcium Phosphate Biomaterial Exhibit Enhanced Macrophage Polarization. Cells.
- (2022). Contact osteogenesis by biodegradable 3D-printed poly(lactide-co-trimethylene carbonate). Biomaterials Research. 1-19.
- (2021). Systemic and local innate immune responses to surgical co-transplantation of mesenchymal stromal cells and biphasic calcium phosphate for bone regeneration. Acta Biomaterialia.
- (2021). Spheroid Coculture of Human Gingiva-Derived Progenitor Cells With Endothelial Cells in Modified Platelet Lysate Hydrogels. Frontiers in Bioengineering and Biotechnology. 13 pages.
- (2021). RvE1 Impacts the Gingival Inflammatory Infiltrate by Inhibiting the T Cell Response in Experimental Periodontitis. Frontiers in Immunology.
- (2021). Ectopic Bone Tissue Engineering in Mice Using Human Gingiva or Bone Marrow-Derived Stromal/Progenitor Cells in Scaffold-Hydrogel Constructs. Frontiers in Bioengineering and Biotechnology. 1-14.
- (2021). Bone regeneration in rat calvarial defects using dissociated or spheroid mesenchymal stromal cells in scaffold-hydrogel constructs. Stem Cell Research & Therapy.
- (2020). Xeno-free spheroids of human gingiva-derived progenitor cells for bone tissue engineering. Frontiers in Bioengineering and Biotechnology. 14 pages.
- (2020). Regulatory T cell phenotype and anti-osteoclastogenic function in experimental periodontitis. Scientific Reports.
- (2020). Influence of platelet storage time on human platelet lysates and platelet lysate-expanded mesenchymal stromal cells for bone tissue engineering. Stem Cell Research & Therapy. 1-18.
- (2020). Inflammatory mediators in saliva and gingival fluid of children with congenital heart defect. Oral Diseases. 1053-1061.
- (2019). Session 9: Biomaterials -Elektrospinning. Biomedizinische Technik. 59-62.
- (2019). Metabolic reprogramming of normal oral fibroblasts correlated with increased glycolytic metabolism of oral squamous cell carcinoma and precedes their activation into carcinoma associated fibroblasts. Cellular and Molecular Life Sciences (CMLS). 1-19.
- (2019). Inflammatory responses and tissue reactions to wood-Based nanocellulose scaffolds. Materials Science and Engineering C: Materials for Biological Applications. 208-221.
- (2019). Impact of humanised isolation and culture conditions on stemness and osteogenic potential of bone marrow derived mesenchymal stromal cells. Scientific Reports. 1-18.
- (2019). Efficacy of copolymer scaffolds delivering human demineralised dentine matrix for bone regeneration . Journal of Tissue Engineering.
- (2019). Cell therapy for orofacial bone regeneration: A systematic review and meta‐analysis. Journal of Clinical Periodontology. 162-182.
- (2019). AXL targeting reduces fibrosis development in experimental unilateral ureteral obstruction. Physiological Reports. 1-20.
- (2018). Adipose-derived and bone marrow mesenchymal stem cells: a donor-matched comparison. Stem Cell Research & Therapy. 168.
- (2018). A three-dimensional hybrid pacemaker electrode seamlessly integrates into engineered, functional human cardiac tissue in vitro. Scientific Reports.
- (2016). Nanodiamond modified copolymer scaffolds affects tumour progression of early neoplastic oral keratinocytes. Biomaterials. 11-21.
- (2016). In vivo host response and degradation of copolymer scaffolds functionalized with nanodiamonds and bone morphogenetic protein 2. Advanced Healthcare Materials. 730-742.
- (2016). Establishment of a bioluminescence model for microenvironmentally induced oral carcinogenesis with implications for screening bioengineered scaffolds. Head and Neck. E1177-E1187.
- (2015). Release and bioactivity of bone morphogenetic protein-2 are affected by scaffold binding techniques in vitro and in vivo. Journal of Controlled Release. 148-157.
- (2013). Identification of two distinct carcinoma-associated fibroblast subtypes with differential tumor-promoting abilities in oral squamous cell carcinoma. Cancer Research. 3888-3901.
- (2021). Systemic monocyte-macrophage response to co-transplanting mesenchymal stromal cells and biphasic calcium phosphate biomaterial for bone regeneration.
- (2015). Expression of integrin α-11 by carcinoma associated fibroblasts modulates oral squamous cell carcinoma behaviour.
- (2015). Different subsets of carcinoma-associated fibroblasts promote oral carcinoma cell invasion by distinct mechanisms.
- (2015). Development of a novel scaffold stimulating stem cells growth, differentiation and bone regeneration.
- (2023). Studieavgift er korttenkt kunnskapspolitikk. Khrono.no.
- (2020). Xeno-free 3D Culture of Mesenchymal Stromal Cells for Bone Tissue Engineering.
- (2015). Bioactive copolymer scaffolds for bone tissue engineering. Efficacy and host response.
- (2015). Bioactive copolymer scaffolds for bone tissue engineering. Efficacy and host response.
- (2019). Effect of human platelet lysate on rat mesenchymal stem cells for bone regeneration – an in vitro study (POSTER).
- (2018). Comparison of donor matched human bone marrow- and adipose-derived mesenchymal stem/stromal cells in Xeno-free conditions.
- (2018). Characterization of Human Gingiva- and PDL-derived Progenitor Cells in 3-D Xeno-free Conditions. .
- (2018). Adipose-Derived Stem Cells for Bone Tissue Engineering.
- (2013). A novel model: Microenvironmentally-induced carcinogenesis for screening bone regeneration scaffolds.
- (2022). Corrigendum: RvE1 Impacts the Gingival Inflammatory Infiltrate by Inhibiting the T Cell Response in Experimental Periodontitis (Front. Immunol., (2021), 12, 664756, 10.3389/fimmu.2021.664756). Frontiers in Immunology.
- (2022). Corrigendum: Ectopic Bone Tissue Engineering in Mice Using Human Gingiva or Bone Marrow-Derived Stromal/Progenitor Cells in Scaffold-Hydrogel Constructs (Front. Bioeng. Biotechnol., (2021), 9, (783468), 10.3389/fbioe.2021.783468). Frontiers in Bioengineering and Biotechnology.
- (2019). The bone regeneration capacity of 3D-printed templates in calvarial defect models: A systematic review and meta-analysis. Acta Biomaterialia. 1-23.
- (2017). Efficacy of humanized Mesenchymal stem cell cultures for bone tissue engineering: a systematic review with a focus on platelet derivatives. Tissue Engineering Part B: Reviews. 552-569.
More information in national current research information system (CRIStin)
2021 - 2025 (Principal Investigator) Immune-driven tissue regeneration (STEMreg) funded by Trond Mohn Foundation Starting Grant: 19.2 million NOK
2021 - 2026 (Principal Investigator) Harnessing regulatory T cells to enhance the efficacy of mesenchymal stem cell-based bone regeneration funded by Research Council of Norway, Young Researcher Talent grant: 8 million NOK
Selected Awards and Fellowships
2021 Meltzer Prize for Outstanding Young Researcher 2020
2021-2022 Fellow of the Momentum Career Development Program, University of Bergen
2016 Best PhD thesis for the year 2015 in the Faculty of Medicine & Dentistry, UiB