Regulating mechanisms in teeth

Signal substances regulate normal functions and defence mechanisms and repair following tissue injury. The aim of the research group is to increase knowledge about mechanisms that control the outcome of injuries in teeth. Teeth in function are normally subjected to external forces, disease and damage, resulting in inflammatory changes in teeth and supporting tissues. Pain, both of chronic and acute character, is often an unwanted side-effect. As teeth are extremely well supplied with nerve fibres, teeth represent an excellent model system to study how nerve tissue is affected by injury and inflammation, and also the effects of nerve tissue on the outcome of tissue injury. By functional studies, inner steering mechanisms that sustain balance in these tissues are investigates. Clinical studies are included in the project.