Publications

Vitova, Milada; Lanta, Vojtech; Cizkova, Maria; Jakubec, Martin; Rise, Frode; Halskau, Øyvind; Bisova, Katerina; Furse, Samuel Robert. The biosynthesis of phospholipids is linked to the cell cycle in a model eukaryote. Biochimica et Biophysica Acta - Molecular and Cell Biology of Lipids 2021 doi: 10.1016/j.bbalip.2021.158965

Khezri R, Holland P, Schoborg TA, Abramovic I, Takats S, Dillard C, Jain A, O’Farrell F et al. (2021) Host autophagy mediates organ wasting and nutrient mobilization for tumor growth. EMBO Journal. 2021 Jul 26:e107336. doi: 10.15252/embj.2020107336. Epub ahead of print.

F Mazloumi Gavgani, M Skuseth Slinning, A Papdiné Morovicz, V Smith Arnesen, D C Turcu, S Ninzima, CS D’Santos and AE Lewis (2021). Nuclear phosphatidylinositol 3,4,5-trisphosphate interactome uncovers an enrichment in nucleolar proteins. Molecular & Cellular Proteomics. 20:100102. doi: 10.1016/j.mcpro.2021.100102. Also in bioRxiv, doi: 10.1101/2020.05.17.100446.

F Mazloumi Gavgani, T Karlsson, IL Tangen, A Papdiné Morovicz, V Smith Arnesen, D C Turcu, S Ninzima, K Spang, C Krakstad, J Guillermet-Guibert and AE Lewis (2021). Nuclear upregulation of class I phosphoinositide 3-kinase p110β correlates with increased 47S rRNA levels in cancer cells. Journal Cell Biology. 134(3):jcs246090. doi: 10.1242/jcs.246090. also in bioRxiv. doi:10.1101/2019.12.20.884122.

Ellul, Rebecca Marie; Kalatzis, Panos G.; Frantzen, Cyril Alexander; Haugland, Gyri Teien; Gulla, Snorre; Colquhoun, Duncan John; Middelboe, Mathias; Wergeland, Heidrun Inger; Rønneseth, Anita. Genomic analysis of pasteurella atlantica provides insight on its virulence factors and phylogeny and highlights the potential of reverse vaccinology in aquaculture. Microorganisms 2021;Volum 9(6) s. – doi:10.3390/microorganisms9061215

Edson, A.J., Hushagen, H.A., Fladmark, K.E. (2020) DJ-1 in astrocytic neuroprotection to oxidative stress. In Oxidative Stress and Dietary Antioxidants in Neurological Diseases Ed Preedy, V. Academic Press. Doi: 10.1007/s12035-019-01667-w

Penna C, Femminò S, Tapparo M, Lopatina T, Fladmark KE, Ravera F, Comità S, Alloatti G, Giusti I, Dolo V, Camussi G, Pagliaro P, Brizzi MF. The Inflammatory Cytokine IL-3 Hampers Cardioprotection Mediated by Endothelial Cell-Derived Extracellular Vesicles Possibly via Their Protein Cargo. Cells. 2020 Dec 23;10(1):13. doi: 10.3390/cells10010013. 

Dobrovolska, Olena; Brilkov, Maxim; Madeleine, Noëlly; Ødegaard-Fougner, Øyvind; Strømland, Øyvind; Martin, Stephen R.; De Marco, Valeria; Christodoulou, Evangelos; Teigen, Knut; Isaksson, Johan; Underhaug, Jarl; Reuter, Nathalie; Aalen, Reidunn B.; Aasland, Rein; Halskau, Øyvind. 2020. The Arabidopsis (ASHH2) CW domain binds monomethylated K4 of the histone H3 tail through conformational selection. The FEBS Journal. 4458-4480. doi: 10.1111/febs.15256

Jakubec, Martin; Maple-Grødem, Jodi; Akbari, Saleha; Nesse, Susanne; Halskau, Øyvind; Mork-Jansson, Astrid Elisabeth. 2020. Plasma-derived exosome-like vesicles are enriched in lyso-phospholipids and pass the blood-brain barrier. PLOS ONE. 1-15. Doi: 10.1371/journal.pone.0232442

Jakubec, Martin; Bariås, Espen; Furse, Samuel Robert; Govasli Larsen, Morten Andreas; George, Vinnit; Turcu, Diana Cornelia; Iashchishyn, Igor A.; Morozova-Roche, Ludmilla A.; Halskau, Øyvind. 2020. Cholesterol-containing lipid nanodiscs promote an α-synuclein binding mode that accelerates oligomerization. The FEBS Journal. Doi: 10.1111/febs.15551

Jakubec, Martin; Totland, Christian; Rise, Frode; Chamgordani, Elahe Jafari; Paulsen, Britt; Maes, Louis; Matheeussen, An; Gundersen, Lise-Lotte; Halskau, Øyvind. 2020. Bioactive metabolites of marine origin have unusual effects on model membrane systems. Marine Drugs. 1-11. Doi: 10.3390/md18020125

Vietri, Marina; Schultz, Sebastian; Bellanger, Aurélie Nathalie Pascale; Jones, Carl; Petersen, Louise I; Raiborg, Camilla; Skarpen, Ellen; Pedurupillay Jesuthasan, Christeen Ramane; Kjos, Ingrid; Kip, Eline; Timmer, Ronny; Jain, Ashish; Collas, Philippe; Knorr, Roland; Grellscheid, Sushma; Kusumaatmaja, Halim; Brech, Andreas; Micci, Francesca; Stenmark, Harald Alfred; Campsteijn, Coen. Unrestrained ESCRT-III drives micronuclear catastrophe and chromosome fragmention. Nature Cell Biology 2020;Volum 22. s. 856-867  Doi: 10.1038/s41556-020-0537-5

Gahan JM, Rentzsch F, Schnitzler CE (2020) The genetic basis for PRC1 complex diversity emerged early in animal evolution. Proc. Nat. Acad. Sci. doi: 10.1073/pnas.2005136117

Tournière O, Dolan D, Richards GS, Sunagar K, Columbus-Shenkar YY, Moran Y, Rentzsch F (2020) NvPOU4/Brain3 functions as a terminal selector gene in the nervous system of the cnidarian Nematostella vectensis. Cell Reports 30: 4473-4489 Doi:10.1016/j.celrep.2020.03.031

Eggestøl, Håvard Øritsland; Lunde, Harald Sæbø; Haugland, Gyri Teien. The proinflammatory cytokines TNF-α and IL-6 in lumpfish (Cyclopterus lumpus L.) -identification, molecular characterization, phylogeny and gene expression analyses. Developmental and Comparative Immunology 2020 ;Volum 106.(103608). Doi: 10.1016/j.dci.2020.103608

Eggestøl, Håvard Øritsland; Lunde, Harald Sæbø; Knutsen, Tim Martin; Haugland, Gyri Teien. Interleukin-1 ligands and receptors in lumpfish (Cyclopterus lumpus L.): molecular characterization, phylogeny, gene expression and transcriptome analyses. Frontiers in Immunology 2020; Volum 11.(501) Suppl. 8 s. – Doi: 10.3389/fimmu.2020.00502

Grøsvik, Kristin; Tesfahun, Almaz Nigatu; Muruzábal-Lecumberri, Izaskun; Haugland, Gyri Teien; Leiros, Ingar; Ruoff, Peter; Kvaløy, Jan Terje; Knævelsrud, Ingeborg; Ånensen, Hilde; Alexeeva, Marina; Sato, Kousuke; Matsuda, Akira; Alseth, Ingrun; Klungland, Arne; Bjelland, Svein. The Escherichia coli alkA Gene Is Activated to Alleviate Mutagenesis by an Oxidized Deoxynucleoside. Frontiers in Microbiology 2020 ;Volum 11. s. – Doi: 10.3389/fmicb.2020.00263

Onischenko, E.*, Noor, E.*, Fischer, J.*, Gillet, L., Wojtynek, M., Vallotton, P., and Weis, K. (2020). Maturation Kinetics of a Multiprotein Complex Revealed by Metabolic Labeling. Cell doi: 10.1016/j.cell.2020.11.001

Edson, A.J., Hushagen, H.A., Frøyset, AK., Elda, I., Khan, E.A., Di Stefano, A., Fladmark, K.E. (2019) Dysregulation in the brain protein profile of zebrafish lacking the Parkinson’s disease related protein DJ-1. Mol. Neurobiol. DOI: 10.1007/s12035-019-01667-w

Jakubec, Martin; Bariås, Espen; Kryuchkov, Fedor; Hjørnevik, Linda Veka; Halskau, Øyvind. 2019. Fast and quantitative phospholipidomic analysis of SH-SY5Y neuroblastoma cell cultures using LC-MS/MS and 31P NMR. ACS Omega. 21596-21603.  Doi: 10.1021/acsomega.9b03463

Torres-Méndez A, Bonnal S, Marquez Y, Roth J, Iglesias M, Permanyer J, Almudí I, O'Hanlon D, Guitart T, Soller M, Gingras AC, Gebauer F, Rentzsch F, Blencowe BJ, Valcárcel J, Irimia M. (2019) A novel protein domain in an ancestral splicing factor drove the evolution of neural microexons. Nat Ecology and Evolution 3: 691-701 Doi: 10.1038/s41559-019-0813-6

Turcu, Diana Cornelia; Lillehaug, Johan R.; Seo, Hee-Chan. SIX3 and SIX6 interact with GEMININ via C-terminal regions. Biochemistry and Biophysics Reports 2019; Volum 20. Doi: 10.1016/j.bbrep.2019.100695

RG Jacobsen, F Mazloumi Gavgani, AJ. Edson, M Goris, A Altanchimeg and AE Lewis (2019) Polyphosphoinositides in the nucleus: Roadmap of their effectors and mechanisms of interaction. Advances in Biological Regulation. 72: 7-21. Doi: 10.1016/j.jbior.2019.04.001

Haugland, Gyri Teien; Kverme, Karen Obrestad; Hannisdal, Rita; Kallekleiv, Marielle; Colquhoun, Duncan John; Lunestad, Bjørn Tore; Wergeland, Heidrun Inger; Samuelsen, Ole Bent. Pharmacokinetic Data Show That Oxolinic Acid and Flumequine Are Absorbed and Excreted Rapidly From Plasma and Tissues of Lumpfish. Frontiers in Veterinary Science 2019 ;Volum 6. Doi: 10.3389/fvets.2019.00394

Kverme, Karen Obrestad; Haugland, Gyri Teien; Hannisdal, Rita; Kallekleiv, Marielle; Colquhoun, Duncan John; Lunestad, Bjørn Tore; Wergeland, Heidrun Inger; Samuelsen, Ole Bent. Pharmacokinetics of florfenicol in lumpfish (Cyclopterus lumpus L.) after a single oral administration. Aquaculture 2019 ;Volum 512. s. 1-7 Doi: 10.1016/j.aquaculture.2019.734279

Vallotton, P., Rajoo, S., Wojtynek, M., Onischenko, E., Kralt, A., Derrer, C.P., and Weis, K. (2019). Mapping the native organization of the yeast nuclear pore complex using nuclear radial intensity measurements. Proc Nat Acad Sci USA 116, 14606-14613. doi: 10.1073/pnas.1903764116

Astroglial DJ-1 over-expression up-regulates proteins involved in redox regulation and is neuroprotective in vivo. Frøyset AK Edson AJ, Gharbi N, Khan EA, Dondorp D, Bai Q, Tiraboschi E, Suster ML, Connolly JB, Burton EA, and Fladmark KE. (2018) Redox Biol. 16:237-247. Doi: 10.1016/j.redox.2018.02.010

Delavari, Behdad; Mamashli, Fatemeh; Bigdeli, Bahareh; Poursoleiman, Atefeh; Karami, Leila; Zolmajd-Haghighi, Zahra; Ghasemi, Atiyeh; Samaei-Daryan, Samaneh; Hosseini, Morteza; Haertle, Thomas; Muronetz, Vladimir I; Halskau, Øyvind; Moosavi-Movahedi, Ali Akbar; Goliaei, Bahram; Rezayan, Ali Hossein; Saboury, Ali Akbar. 2018. A biophysical study on the mechanism of interactions of DOX or PTX with α-lactalbumin as a delivery carrier. Scientific Reports. 1-21. Doi: 10.1038/s41598-018-35559-1

Dobrovolska, Olena; Brilkov, Maxim; Ødegård‑Fougner, Øyvind; Aasland, Rein; Halskau, Øyvind. 2018. 1H, 13C, and 15N resonance assignments of CW domain of the N-methyltransferase ASHH2 free and bound to the mono-, di- and tri-methylated histone H3 tail peptides. Biomolecular NMR Assignments. 215-220. Doi: 10.1007/s12104-018-9811-x

Buskin, Adriana; Zhu, Lili; Chichagova, Valeria; Basu, Basudha; Mozaffari-Jovin, Sina; Dolan, David; Droop, Alastair; Collin, Joseph; Bronstein, Revital; Mehrotra, Sudeep; Farkas, Michael; Hilgen, Gerrit; White, Kathryn; Pan, Kuan-Ting; Treumann, Achim; Hallam, Dean; Bialas, Katarzyna; Chung, Git; Mellough, Carla; Ding, Yuchun; Krasnogor, Natalio; Przyborski, Stefan; Zwolinski, Simon; Al-Aama, Jumana; Alharthi, Sameer E.; Xu, Yaobo; Wheway, Gabrielle; Szymanska, Katarzyna; McKibbin, Martin; Inglehearn, Chris F; Elliott, David J.; Lindsay, Susan; Ali, Robin R.; Steel, David H; Armstrong, Lyle; Sernagor, Evelyne; Urlaub, Henning; Pierce, Eric; Luhrmann, Reinhard; Grellscheid, Sushma; Johnson, Colin A.; Lako, Majlinda.  Disrupted alternative splicing for genes implicated in splicing and ciliogenesis causes PRPF31 retinitis pigmentosa. Nature Communications 2018; Volum 9.(1) Doi: 10.1038/s41467-018-06448-y

da Silva, Paulo F.L.; Ogrodnik, Mikolaj; Kucheryavenko, Olena; Glibert, Julien; Miwa, Satomi; Cameron, Kerry; Ishaq, Abbas; Saretzki, Gabriele; Grellscheid, Sushma; Nelson, Glyn; von Zglinicki, Thomas.  The bystander effect contributes to the accumulation of senescent cells in vivo. Aging Cell 2018; Volum 00:e12848. s. 1-15 Doi: 10.1111/acel.12848

F Mazloumi Gavgani, V Smith Arnesen, RG Jacobsen, C Krakstad, EA Hoivik, AE Lewis (2018). Class I Phosphoinositide 3-Kinase PIK3CA/p110α and PIK3CB/p110β Isoforms in Endometrial Cancer. Int J Mol Sci. 19(12). pii: E3931. doi: 10.3390/ijms19123931.

Eggestøl, Håvard Øritsland; Lunde, Harald Sæbø; Rønneseth, Anita; Fredman, David; Petersen, Kjell; Mishra, Charitra Kumar; Furmanek, Tomasz; Colquhoun, Duncan John; Wergeland, Heidrun Inger; Haugland, Gyri Teien. Transcriptome-wide mapping of signaling pathways and early immune responses in lumpfish leukocytes upon in vitro bacterial exposure. Scientific Reports 2018 ;Volum 8:5261. Suppl. 65 sider s. 1-14 Doi: 10.1038/s41598-018-23667-x

Ellul, Rebecca Marie; Walde, Cecilie Sviland; Haugland, Gyri Teien; Wergeland, Heidrun Inger; Rønneseth, Anita.  Pathogenicity of Pasteurella sp. in lumpsuckers (Cyclopterus lumpus L.). Journal of Fish Diseases 2018; Volum 42.(1) s. 35-46 Doi: 10.1111/jfd.12905

Rajoo, S., Vallotton, P., Onischenko, E., and Weis, K. (2018). Stoichiometry and compositional plasticity of the yeast nuclear pore complex revealed by quantitative fluorescence microscopy. Proc Nat Acad Sci USA 115, E3969-E3977. Doi: 10.1073/pnas.1719398115