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University of Bergen
ProtMetD: Protein Modifications, Metabolism and Disease

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Forskere ved MBI oppdager viktigheten av vitamin B3

Forskerne Nick Love, Nadine Pollak, Christian Döelle og Mark Niere fra Zieglergruppen har funnet ut at siste stadie i omdannelsen av vitamin B3 til molekylet NADP er avgjørende for den embryoniske utviklingen av dyr.

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The enzyme NAD kinase is responsible for the final step in the conversion of vitamin B3 to NADP (used collectively for NADPH and NADP+). NADPH is an important molecule, which connects metabolism and various defence mechanisms. These include the immune response, detoxification reactions and the "fueling" of natural antioxidant systems.

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