Publications Lynagh Group
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Seljeset S, Sintsova O, Wang Y, Harb HY, Lynagh T (2024). Constitutive activity of ionotropic glutamate receptors via hydrophobic substitutions in the ligand-binding domain. Structure. 32:966-978.e6. https://www.cell.com/structure/fulltext/S0969-2126(24)00127-8
Kalienkova V, Dandamudi M, Paulino C, Lynagh T (2024). Structural basis for excitatory neuropeptide signaling. Nat Struct Mol Biol 31:717-726. https://www.nature.com/articles/s41594-023-01198-y
Rosano G, Barzasi A, Lynagh T (2024). Loss of activation by GABA in vertebrate delta ionotropic glutamate receptors. Proc Natl Acad Sci USA 121:e2313853121. https://www.pnas.org/doi/10.1073/pnas.2313853121
Marti-Solans J, Børve A, Bump P, Hejnol A, Lynagh T (2023). Peripheral and central employment of acid-sensing ion channels during early bilaterian evolution. eLife 12:e81613. https://doi.org/10.7554/eLife.81613
Dandamudi M, Hausen H, Lynagh T (2022). Comparative analysis defines a broader FMRFamide-gated sodium channel family and determinants of neuropeptide sensitivity. J Biol Chem 298:1020086. https://www.jbc.org/article/S0021-9258(22)00527-0/fulltext
Lynagh T, Kiontke S, Meyhoff-Madsen M, Gless BH, Johannesen J, Kattelmann S, Christiansen A, Dufva M, Laustsen AH, Devkota K, Olsen CA, Kümmel D, Pless SA, Lohse B (2020). Peptide Inhibitors of the α-Cobratoxin-Nicotinic Acetylcholine Receptor Interaction. J Med Chem 63:13709-13718. https://pubs.acs.org/doi/10.1021/acs.jmedchem.0c01202