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Latest publications:

B. T. Mathiesen#, M. Ohta#, B. P. De Magalhaes, C. Castelletti, V. Perria, L. Christiaen* and N. Ohta*. A simple inland culture system provides insights into ascidian post-embryonic developmental physiology. Open Biol. 2025 Jan;15(1):240340. doi: 10.1098/rsob.240340. 

Naoyuki Ohta, and Lionel ChristiaenCellular remodeling and JAK inhibition promote zygotic gene expression in the Ciona germline. 2024. EMBO Rep. 2024 May;25(5):2188-2201. doi: 10.1038/s44319-024-00139-0. Epub 2024 Apr 22. 

A. Tjärnberg, M. Beheler-Amass, C.A. Jackson, L.A. Christiaen, D. Gresham, R. Bonneau, Structure Primed Embedding on the Transcription Factor Manifold Enables Transparent Model Architectures for Gene Regulatory Network and Latent Activity Inference. 2023. Genome Biol 2024 Jan 18;25(1):24. doi: 10.1186/s13059-023-03134-1. BioRxiv. 2023.02.02.526909.

Burcu Vitrinel, Christine Vogel, Lionel ChristiaenRnf149-related is an FGF/MAPK-independent regulator of pharyngeal muscle fate specification. 2023. Int J Mol Sci. 24(10):8865. doi: 10.3390/ijms24108865. BioRxiv 2022.01.07.475354; doi: https://doi.org/10.1101/2022.01.07.475354

Song M, Yuan X, Racioppi C, Leslie M, Stutt N, Aleksandrova A, Christiaen L, Wilson MD, Scott IC. GATA4/5/6 family transcription factors are conserved determinants of cardiac versus pharyngeal mesoderm fate. 2022. Sci Adv. doi: 10.1126/sciadv.abg0834. PMCID: PMC8916722.

Bernadskaya YY, Yue H, Copos C, Christiaen L, Mogilner A (2021) Supracellular organization confers directionality and mechanical potency to migrating pairs of cardiopharyngeal progenitor cells. Elife. 29;10:e70977

Nomaru H, Liu Y, De Bono C, Righelli D, Cirino A, Wang W, Song H, Racedo SE, Dantas AG, Zhang L, Cai CL, Angelini C, Christiaen L, Kelly RG, Baldini A, Zheng D, Morrow BE (2021) Single cell multi-omic analysis identifies a Tbx1-dependent multilineage primed population in murine cardiopharyngeal mesoderm. Nat Commun. 17;12(1):6645

Tjärnberg A, Mahmood O, Jackson CA, Saldi GA, Cho K, Christiaen L, Bonneau RA (2021) Optimal tuning of weighted kNN- and diffusion-based methods for denoising single cell genomics data. PLoS Comput Biol., 17(1):e1008569

Lowe EK, Racioppi C, Peyriéras N, Ristoratore F, Christiaen L, Swalla BJ, Stolfi A (2021) A cis-regulatory change underlying the motor neuron-specific loss of Ebf expression in immotile tunicate larvae. Evol Dev., 23(2):72-85

Ohta N, Kaplan N, Ng JT, Gravez BJ, Christiaen L (2020) Asymmetric Fitness of Second-Generation Interspecific Hybrids Between Ciona robusta and Ciona intestinalis. G3: Genes, Genomes, Genetics 10(8):2697-2711

Vitrinel B, Iannitelli DE, Mazzoni EO, Christiaen L, Vogel C (2020) Simple Method to Quantify Protein Abundances from 1000 Cells. ACS Omega, 5(25):15537-15546

Shim WJ, Sinniah E, Xu J, Vitrinel B, Alexanian M, Andreoletti G, Shen S, Sun Y, Balderson B, Boix C, Peng G, Jing N, Wang Y, Kellis M, Tam PPL, Smith A, Piper M, Christiaen L, Nguyen Q, Bodén M, Palpant NJ (2020) Conserved Epigenetic Regulatory Logic Infers Genes Governing Cell Identity. Cell Syst., 11(6):625-639