Vilde Brecke

PhD Project Title: Zooming in and out on brain structure in obsessive-compulsive disorder

This PhD project aims to investigate the relationship between brain imaging estimates, demographic variables, and clinical measures in individuals with obsessive-compulsive disorder (OCD). The project comprises three studies that explore potential differences in brain structures between individuals experiencing symptoms of obsessive thoughts and compulsive behaviors that meet the clinical criteria for OCD, compared to individuals without clinically significant psychological symptoms.

Additionally, we seek to understand the factors contributing to these potential differences in brain structure. Specifically, we focus on the volume of selected brain regions and the fiber tracts that serve as communication highways within the brain. Two of the studies also investigate how these brain structures may change following successful treatment.

By gaining a deeper understanding of the relationship between the brain and behavior, we aim to improve our ability to support individuals struggling with debilitating psychological symptoms. This research holds promise for enhancing our knowledge and treatment approaches for conditions such as OCD, which can significantly impact the well-being of affected individuals.