Doctoral theses

Supervisor Aurora Martinez

• Maria Teresa Bezem, 2022, UiB, "Functionalization of Nanoparticles with Tyrosine Hydroxylase"
• Karina Skjervheim Prestegård, 2022, UiB, "Understanding proteostasis dysregulation in phenylketonuria – a paradigm disease for inborn error of metabolism"
• Fredrik Gullaksen Johannesen, 2022, UiB, "Characterization of the functionality of nanoparticles and nanodiscs complexed with dopamine-associated proteins"
• Kunwar Jung K C, 2021, UiB "Regulatory post-translational modifications and protein-protein interactions involved in function and proteostasis of aromatic amino acid hydroxylases"
• Oscar Aubi Catevilla, 2016, UiB, “Discovery of small-molecule activity modulators of bacterial and human phenylalanine hydroxylase”
• Helene Bustad Johannessen (Cosupervisor with Prof. Sverre Sandberg), 2016, UiB, “Characterization of Hydroxymethylbilane Synthase and Pharmacological Chaperone Treatment for Acute Intermittent Porphyria”
• Alexander Sauter, 2015, UiB, “Contact-dependent culture dish interactions during in vitro generation of monocyte-derived dendritic cells”
• Anne Baumann, 2013, UiB, "The peripheral binding of proteins to phospholipid membranes, with focus on α-lactalbumin and Tyrosine hydroxylase"
• Marte I. Flydal, 2012, UiB, ”Structure, function and regulation of non-mammalian forms of phenylalanine hydroxylase”
• Lars Skjærven, 2011, UiB, “A computational approach for probing conformational dynamics, flexibility and allostery in the GroEL chaperone”
• Ana Calvo, 2010, UiB, “Function and regulation of phenylalanine and tyrosine hydroxylases from human and Caenorhabditis elegans”
• Khanh K. Dao, 2010, UiB, “Conformationa Dynamics, Stability and Domain Communication in Regulatory Subunit of cAMP dependent Protein Kinase. Effect of Cyclic Nucleotide Binding”
• Jessica S.-Liberles, 2008, UiB, “Evolution of Structure and Function in Phenylalanine Hydroxylase. With the Regulatory Properties in Sight”
• Frederico F. Miranda, 2005, University of Coimbra, Portugal and UiB, “Phenylalanine hydroxylase. Studies on residues relevant for regulation and catalysis”
• Øyvind Halskau, 2005, UiB, Structure and dynamics of the peripheral protein lactalbumin in relation to its membrane binding capability”
• Knut Teigen, 2004, UiB, “Structural and Functional Aspects of Pterin-Binding Enzymes - A Nuclear Magnetic Resonance Spectroscopy and Molecular Modeling Study”
• Matthías Thórólfsson, 2003, UiB, “Biophysical Studies on Human Phenylalanine Hydroxylase: Stability and Regulation by L-Phenylalanine”

Supervisor Knut Teigen

• Magnus Hole, 2015, UiB, “A study of structure-function-stability relationships in tyrosine hydroxylase”
• Åge A. Skjevik, 2013, UiB, “A study of lipid bilayer dynamics and interactions with ligands"