Srdjan's Projects
Main content
The projects led by Professor Srdjan Djurovic are intimately connected with SFF NORMENT and KG Jebsen Centre for Psychosis Research, which is a major collaborative effort studying clinical characteristics, neurocognitive functioning and brain biology of psychotic disorders. As such the research spans the Department of Clincial Science, University of Bergen and Department of Medical Genetics, University of Oslo.
Some of the projects underway are as follows:
Projects
- Identification of the hidden heritability of severe mental disorders
- Identifying the polygenic basis of the human brain and neurodevelopmental disorders
- Identifying causal variants in candidate regions
- Human induced pluripotent stem cell (hiPSC) technologies in psychiatric molecular genetics
- Prediction of longitudinal outcome and brain phenotype by polygenic scores
- Identification of genetic loci associated with neurocognitive and MR phenotypes and implications for disease mechanisms in severe mental disorders
- Biobanking, database, sample prep, QC
Cooperation
It is of vital importance to base genetic discovery on large samples, which is difficult to obtain without international collaboration. The Psychiatric Molecular Genetics Group participates in several large European studies of schizophrenia genetics, the SGENE-plus group (coordinated by deCODE, and including research groups as well as samples from England, Germany, Finland, Denmark, Iceland, Scotland) and Scandinavian Collaboration on Psychiatric Etiology (SCOPE),
Further, the Psychiatric Molecular Genetics Group is a member of the Psychiatric Genetics Consortium (PGC) which includes all GWAS studies in psychiatric genetics, as well as European IPSC Consortium for Neuropsychiatric Disorders (EURICND)