Publications
Main content
MemBrain is a new research group starting 2024. Our publications will be linked here.
Some previous relevant publications by the PI include:
Biallelic NAA60 variants with impaired N-terminal acetylation capacity cause autosomal recessive primary familial brain calcifications.
Chelban V ✉️, Aksnes H ✉️, Maroofian R, LaMonica LC, Seabra L, Siggervåg A, Devic P, Shamseldin HE, Vandrovcova J, Murphy D, Richard AC, Quenez O, Bonnevalle A, Zanetti MN, Kaiyrzhanov R, Salpietro V, Efthymiou S, Schottlaender LV, Morsy H, Scardamaglia A, Tariq A, Pagnamenta AT, Pennavaria A, Krogstad LS, Bekkelund ÅK, Caiella A, Glomnes N, Brønstad KM, Tury S, Moreno De Luca A, Boland-Auge A, Olaso R, Deleuze JF, Anheim M, Cretin B, Vona B, Alajlan F, Abdulwahab F, Battini JL, İpek R, Bauer P, Zifarelli G, Gungor S, Kurul SH, Lochmuller H, Da'as SI, Fakhro KA, Gómez-Pascual A, Botía JA, Wood NW, Horvath R, Ernst AM, Rothman JE, McEntagart M, Crow YJ, Alkuraya FS, Nicolas G; SYNaPS Study Group; Arnesen T ✉️, Houlden H ✉️.
Nat Commun. 2024 Mar 13;15(1):2269. doi: 10.1038/s41467-024-46354-0. PMID: 38480682
- Popular scientific summary here.
NATs at a glance.
Aksnes H✉️, McTiernan N, Arnesen T✉️.
J Cell Sci. 2023 Jul 15;136(14):jcs260766. doi: 10.1242/jcs.260766. Epub 2023 Jul 18. PMID: 37462250
- Review with accessible poster.
Protein Termini 2022: central roles of protein ends.
Arnesen T✉️, Aksnes H✉️, Giglione C✉️.
Trends Biochem Sci. 2023 Jun;48(6):495-499. doi: 10.1016/j.tibs.2023.02.008. Epub 2023 Mar 29. PMID: 36997368
- Meeting report from EMBO/ISPT meeting 2022.
Actin finally matures – uncovering the machinery and the impact
Arnesen T✉️ and Aksnes H✉️
Trends Biochem Sci 2023 PMID: 36804256
- Commentary on: Haahr P et al., Science 2022 10.1126/science.abq5082
Expanded in vivo substrate profile of the yeast N-terminal acetyltransferase NatC
Van Damme P✉️, Osberg C S, Jonckheere V, Glomnes N, Gevaert K, Arnesen T and Aksnes H✉️
J Biol Chem, 2023 299(2):102824. PMID: 36567016
- Popular scientific summary here.
Missense NAA20 variants impairing the NatB protein N-terminal acetyltransferase cause autosomal recessive developmental delay, intellectual disability, and microcephaly.
Morrison J*, Altuwaijri NK*, Brønstad K*, Aksnes H*, Alsaif HS, Evans A, Hashem M, Wheeler PG, Webb BD, Alkuraya FS, Arnesen T.
Genet Med. 2021 Nov;23(11):2213-2218. doi: 10.1038/s41436-021-01264-0. Epub 2021 Jul 6. PMID: 34230638
- Popular scientific summary here.
Efficient and crucial quality control of HAP1 cell ploidy status
Beigl TB, Kjosås I, Seljeseth E, Glomnes N, Aksnes H✉️
Biol Open. 2020 Nov 12;9(11):bio057174. doi: 10.1242/bio.057174. PMID: 33184093
- Popular scientific summary here.
- Attention/media by Horizon Discovery and Journal of cell science.
Exploiting the potential of commercial digital holographic microscopy by combining it with 3D matrix cell culture assays
Hellesvik M, Øye H, Aksnes H✉️
Sci Rep. 2020 Sep 7;10(1):14680. doi: 10.1038/s41598-020-71538-1.PMID: 32895419
- Popular scientific summary here.
- Attention: Application note by Phase Holographic Imaging AB.
N-terminal acetylation of actin by NAA80 is essential for structural integrity of the Golgi apparatus
Beigl TB, Hellesvik M, Saraste J, Arnesen T, Aksnes H✉️
Exp Cell Res. 2020 May 15;390(2):111961. doi: 10.1016/j.yexcr.2020.111961. Epub 2020 Mar 21.PMID: 32209306
- Popular scientific summary here.
Co-translational, Post-translational, and Non-catalytic Roles of N-Terminal Acetyltransferases
Aksnes H✉️, Ree R, Arnesen T✉️.
Mol Cell. 2019 Mar 21;73(6):1097-1114. Review. PMID: 30878283
Molecular determinants of the N-terminal acetyltransferase Naa60 anchoring to the Golgi membrane
Aksnes H, Goris M, Strømland Ø, Drazic A, Waheed Q, Reuter N, Arnesen T.
J Biol Chem. 2017 Apr 21;292(16):6821-6837. PMID: 28196861
- Popular scientific summary here.
Holding it together: Naa60 at the Golgi
Aksnes H, Marie M, Arnesen T.
Oncotarget. 2015 Jun 30;6(18):15726-7. PMID: 26164078
An organellar Nα-acetyltransferase, Naa60, acetylates cytosolic N termini of transmembrane proteins and maintains Golgi integrity
Aksnes H, Van Damme P, Goris M, Starheim KK, Marie M, Støve SI, Hoel C, Kalvik TV, Hole K, Glomnes N, Furnes C, Ljostveit S, Ziegler M, Niere M, Gevaert K, Arnesen T.
Cell Rep. 2015 Mar 3;10(8):1362-74. PMID: 25732826
- Popular scientific summary here.
- Attention in Cell Reports blog.