Ri

Paraneoplastic Neurological Syndromes (PNS) associated with this antibody:
- Brainstem encephalitis (incl. opsoclonus-myoclonus-syndrome)
- Cerebellar ataxia

Most frequently associated tumors:
- Breast cancer
- Small-cell lung cancer
- Medullary carcinoma of the thyroid gland

The antigen target of anti-Ri is unknown. In cerebral cortex neuronal extract, anti-Ri reacts with two antigens at 55 kDa and 80 kDa. In cerebellar sections anti-Ri shows a similar staining pattern like anti-Hu.