Tr

Paraneoplastic Neurological Syndromes (PNS) associated with this antibody:
- Cerebellar truncal and limb ataxia

Most frequently associated tumors:
- Hodgkin Lymphoma

DNER = Delta/Notch-like epidermal growth factor-related receptor is the target antigen of autoantibody Tr. Anti-Tr antibodies are defined by a specific staining pattern in cerebellar tissue that is characterized by punctate immunoreactivity in both the dendritic tree and soma of Purkinje neurons but not in their axons. [PMID: 25745634]