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Women with a normal weight first offspring and a small second offspring have increased risk of cardiovascular mortality

A new study from the University of Bergen reveals that including offspring birthweight information from women’s subsequent births, is helpful in identifying a woman's long-term risk of dying from cardiovascular causes.

Foto av gravid mage og hender som holder rundt magen
The researchers found that women with a normal weight first offspring and a small second offspring had increased risk of cardiovascular mortality, while reduced risk if the second offspring was large.
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Knowledge of the association between offspring birthweight and long-term maternal cardiovascular disease (CVD) mortality is often based on first-born infants without considering women’s consecutive births.

"These possible relations are also less closely studied among women with term deliveries", says Yeneabeba Sima, PhD Candidate at the Department of Global Public Health and Primary Care, UiB, and the first writer of the article that is newly published in the American Journal of Epidemiology.

Using linked data from the Medical Birth Registry and Cause of Death Registry, the researchers evaluated long-term CVD mortality by offspring birthweight patterns among women with spontaneous and induced term deliveries from 1967-2020.

"We found that women with a normal weight first offspring and a small second offspring had increased risk of cardiovascular mortality, while reduced risk if the second offspring was large."

This was true for women with both spontaneous and clinician-initiated deliveries.

"Changes in offspring birthweight quartiles from first to second pregnancy offer important information on heterogeneity in women's future risk of CVD death", the researcher concludes.

Read this article here: https://academic.oup.com/aje/article-lookup/doi/10.1093/aje/kwad075