Projects

Pharmacological targeting of signaling and metabolic pathways in cancer

• SIRT1 and p53 in leukemia
• Notch signaling pathway in myeloid disease
• Energy metabolism of myeloid neoplasia

New imaging probes development

• Nitroreductase based near-infrared imaging platform
• Nanoparticles-based probes for MRI

Role of microenvironment in cancer

• Generation of artificial bone marrow models
• Microenvironmental factors in AML and MDS

Drug delivery with micro and nanoparticles

• Enhanced chemotherapy through sonoporation of microbubbles
• Nanoparticulate gene and drug delivery vectors