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University of Bergen
Translational molecular imaging in cancer

Publications

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  1. Helland O, Popa M, Vintermyr OK, Molven A, Gjertsen BT, Bjørge L, McCormack E. First in-mouse development and application of a surgically relevant xenograft model of ovarian carcinoma. PLoS One. 2014 Mar 4;9(3):e89527

  2. Poli A, Wang J, Domingues O, Planagumà J, Yan T, Rygh CB, Skaftnesmo KO, Thorsen F, McCormack E, Hentges F, Pedersen PH, Zimmer J, Enger PØ, Chekenya M. Targeting glioblastoma with NK cells and mAb against NG2/CSPG4 prolongs animal survival. Oncotarget. 2013 Sep;4(9):1527-46.

  3. Qu Y, Oyan AM, Liu R, Hua Y, Zhang J, Hovland R, Popa M, Liu X, Brokstad KA,Simon R, Molven A, Lin B, Zhang WD, McCormack E, Kalland KH, Ke XS. Generation of prostate tumor-initiating cells is associated with elevation of reactive oxygen species and IL-6/STAT3 signaling. Cancer Res. 2013 Dec 1;73(23):7090-100

  4. Kotopoulis S, Delalande A, Popa M, Mamaeva V, Dimcevski G, Gilja OH, Postema M, Gjertsen BT, McCormack E. Sonoporation-enhanced chemotherapy significantly reduces primary tumour burden in an orthotopic pancreatic cancer xenograft. Mol Imaging Biol. 2014 Feb;16(1):53-62

  5. Lee J, Li M, Milwid J, Dunham J, Vinegoni C, Gorbatov R, Iwamoto Y, Wang F, Shen K, Hatfield KJ, Enger M, Shafiee S, McCormack E, Ebert B, Weissleder R, Yarmush M, Parekkadan B. Proc Natl Acad Sci U S A. 2012 Nov 27;109(48):19638-43

  6. Jarzabek MA, Huszthy PC, Skaftnesmo KO, McCormack E, Prehn JH, Bjerkvig R, Byrne AT. In vivo bioluminescence imaging validation of a human biopsy-derived orthotopic mouse model of Glioblastoma Multiforme. Mol. Imaging (2013) Mar 1;12(2):1- 12.

  7. Gausdal G, Wergeland A, Skalvland J, Nguyen E, Pendino F, Herfindal L, Kleppe R, Rouhee N, McCormack E, Havemann U, Schwede F, Bruserud Ø, Gjertsen BT, Lanotte M, Segal-Bendirdjian E, Døskeland SO. Cyclic AMP can promote APLprogression and protect myeloid leukemia cells against anthracycline induced apoptosis. Cell Death Dis. (2013) Feb 28;4:e516.

  8. Qi Y, Li WC, Hellem MR, Kari Rostad K, McCormack E, Oyan AM, Kalland KH, Ke XS MiR--182 and miR--203 induce mesenchymal to epithelial transition and self-sufficiency of growth signals via repressing SNAI2 in prostate cells. Int J Cancer. (2013) Aug 1;133(3):544-55.

  9. Brendsdal Forthun R, SenGupta T, Skjeldam HK, Lindvall JM, McCormack E, Gjertsen BT, Nilsen H. Effectors and suppressors of valproic acid HDAC inhibitor function revealed by validation of mammalian –omics data in C. elegans. PLoS One (2012);7(11):e48992.

  10. Hjelle SM, Sulen A, Øye OK, Jørgensen K, McCormack E, Hollund BE and Gjertsen BT. Leucocyte p53 protein biosignature through standard-aligned, two- dimensional immunoblotting. J Proteomics (2012) Dec 5;76 Spec No.:69-78.

  11. Silden E, Hjelle SM, Sulen A, Wergeland L, Bourdon JC, Micklem D, McCormack E and Gjertsen BT. Expression of TP53 isoforms p53β or p53γ Increases chemosensitivity in TP53null cell lines. PLoS One (2013);8(2):e56276

  12. Mujic M, Delalande A, Kotopoulis S, Sulen A, McCormack E, Gilja OH, Postema M, Gjertsen BT. Diagnostic Ultrasound combined with microbubbøes modulates cell stress protein signalling pathways in peripheral blood leukocytes. In Press 2013

  13. McCormack E, Adams KJ, Hassan NJ, Kotian A, Lissin NM, Sami M, Mujić M, Osdal T, Gjertsen BT, Baker D, Powlesland AS, Aleksic M, Vuidepot A, Morteau O, Sutton DH, June CH, Kalos M, Ashfield R and Jakobsen BK. Bi-Specific TCR-anti CD3 Redirected T cell Targeting of NY-ESO-1 and LAGE-1 Positive Tumors. Cancer Immunol. Immunother. (2013) Apr;62(4):773-85

  14. McCormack E, Mujic M, Osdal T, Bruserud Ø, Gjertsen BT. In vivo time-domain near infra-red imaging of multiplexed monoclonal antibodies provide accurate disease staging and therapeutic monitoring in preclinical models of acute myeloid leukemia. Blood (2013) Feb 14;121(7):e34-42.

  15. McCormack E, Silden E, West RM, Pavlin T, Micklem DR, Lorens JB, Haug BE, Cooper ME, Gjertsen BT. Nitroreductase, a near infrared reporter platform for in vivo time-domain optical imaging of metastatic cancer. Cancer Res. (2013) Feb 15; 73(4):1276-1286

  16. Mujic M, Kotopoulis S, Delalande A, Enger M, Gilja OH, McCormack E, Postema M, Gjertsen BT. Flow cytometric characterisation and sorting of microbubble ultrasound contrast reagents. Marine and Medical Research (2012), 11:181-193

  17. Karlsen TV, McCormack E, Mujic M, Tenstad O, Wiig H. Minimally invasive quantification of lymph flow in mice and rats by imaging depot clearance of near-infrared albumin. Am J Physiol Heart Circ Physiol. (2012) Jan;302(2):H391-401

  18. McCormack E, Haaland I, Venås G, Brendsdal Forthun R, Huseby S, Gausdal G, Knappskog S, Micklem DR, Lorens JB, Bruserud Ø, Gjertsen BT. Synergistic induction of p53 mediated apoptosis by valproic acid and nutlin-3 in acute myeloid leukemia. Leukemia. (2012) May;26(5):910-7

  19. Ke X, Li W, Hovland H, Qu Y, Liu R, McCormack E, Thorsen F, Rotter V, AkslenLA Oyan AM, Kalland KH. Reprogramming of cell junction modules during stepwise epithelial to mesenchymal transition and early malignant transformation in a prostate cell model. Exp Cell Res. (2011) Jan 15;317(2):234-47

  20. Wang J, Daphu I, Pedersen PH, Miletic H, Hovland R, Mørk S, Bjerkvig R, Tiron C, McCormack E, Micklem D, Lorens JB, Immervoll H, Thorsen F. A novel brain metastases model developed in immunodeficient rats closely mimics the growth of metastatic brain tumours in patients. Neuropathol Appl Neurobiol. (2011) Feb;37(2):189-205.

  21. Torsvik A, Molven A, Røsland GV, Svendsen A, Primon M, Sobala E, McCormack E, et al. Spontaneous Malignant Transformation of human Mesenchymal Stem Cells reflects cross-contamination; putting the research field on track. Cancer Res. (2010) Aug 1;70(15):6393-6. Epub 2010 Jul 14.

  22. Gjerdrum C, Tiron C, Høiby T, Stefansson I, Haugen H, Sandal T, Collett K, Lid S, McCormack E, Gjertsen BT, Micklem DR, Akslen LA, Glackind C, and Lorens JB. Axl is an essential epithelial-to-mesenchymal transition-induced regulator of breast cancer metastasis and patient survival. Proc Natl Acad Sci U S A. (2010) Jan 19;107(3):1124-9.

  23. Erikstein BS, McCormack E, Tronstad KJ, Schwede F, Berge R, Gjertsen BT. Protein kinase A activators and the pan-PPAR agonist tetradecylthioacetic acid elicit synergistic anti-leukaemic effects in AML through CREB. Leuk. Res. (2010) Jan;34(1):77-84

  24. McCormack E, Skavland J, Mujić M, Bruserud Ø, Gjertsen BT. Lentinan: Haematopoietic, immunological and efficacy studies in a syngeneic model of acute myeloid leukaemia. Nutr. Cancer. (2010) Jul;62(5):574-83.

  25. McCormack E, Hofmann M, Mujić M, Roßberg M, Bernd A, Bereiter-Hahn J, Gjertsen BT, Wiig H and Kippenberger S. Increased plasma colloid osmotic pressure facilitates the uptake of therapeutic macromolecules in a xenograft tumor model 
Neoplasia. (2009); 11(8):812-22

  26. Røsland GV, Svendsen A, Torsvik A, Sobala E, McCormack E, Immervoll H, Mysliwietz J, Tonn JC, Goldbrunner R, Lønning PE, Bjerkvig R, Schichor C. Long-term Cultures of Bone Marrow-Derived Human Mesenchymal Stem Cells Frequently Undergo Spontaneous Malignant Transformation. Cancer Res. (2009);69(13):5331-9
13.10.2014