Doctoral candidates

The MSCA doctoral network TargetRNA will train a cohort of 16 doctoral candidates (DCs) in an intersectoral, international and interdisciplinary setting with the aim to advance the field of RNA-ligand design.

Main content

Currently we are iniviting applications for DC5 only.

Overview of the doctoral projects - click to read more!

Host	Project title
AZ	DC 1: AI-guided design of preQ1-II and SAM-III riboswitch ligands (WP2)
DTU	DC 2: Fragment-based ligand discovery for the preQ1-II and SAM-III riboswitches (WP2)
DTU	DC 3: Discovery of recruiters of bacterial endoribonucleases (WP2, 3)
DTU	DC 4: Hit discovery and structural studies of riboswitch-ligand complexes using NMR and X-ray crystallography (WP1 and 2)
GUF	DC 5: Targeting RNA to reshape the gut microbiome (WP3)
GUF	DC 6: Characterization of riboswitch-ligand interactions using NMR spectroscopy and other biophysical methods (WP1, 2 and 3)
IIT	DC 7: Design of compounds targeting the group II intron of Enterobacteriales and Candida (WP2)
MUAS	DC 8: Mode of action studies (WP3)
RU	DC 9: Methods to study ligand-RNA target engagement in cellulo (WP3)
UB	DC 10: Lead finding and structural characterization of the 5’-UTR of ompA of A. baumannii using fragment screening and application of paramagnetic NMR restraints (WP1 and 2)
UniCA	DC 11: Design, synthesis and biological evaluation of RNA ligands targeting the SAM-I/IV riboswitch (WP2, 3)
UiB	DC 12: Characterization of RNA-ligand interactions using X-ray crystallography and other biophysical methods (WP1, 2 and 3)
UiB	DC 13: Virtual screening and design of riboswitch ligands (WP2)
UiB	DC 14: Design and synthesis of ligands for the FMN riboswitch and the 5’-UTR of ompA (WP2)
UiB	DC 15: Establishing a toolbox of warheads for covalent targeting of RNA (WP2)
UU	DC 16: Structural characterization of group II introns from Enterobacterales and Candida species and the 5’UTR of ompA bound to inhibitors using cryo-EM (WP1, 3)

25.11.2024