Malignancies in childhood
Main content
200 children get cancer every year in Norway. Continuous systematic clinical research is performed to increase survival, reduce side effects and personalize the treatment.
PhD dissertations
Peer review publications
- Heymer EJ, Hawkins MM, Winter DL, Teepen JC, Sunguc C, Ronckers CM, Allodji RS, Alessi D, Sugden E, Belle FN, Bagnasco F, Byrne J, Bárdi E, Garwicz S, Grabow D, Jankovic M, Kaatsch P, Kaiser M, Michel G, Schindera C, Haddy N, Journy N, Česen Mazić M, Skinner R, Kok JL, Gunnes MW, Wiebe T, Sacerdote C, Maule MM, Terenziani M, Jakab Z, Winther JF, Lähteenmäki PM, Zadravec Zaletel L, Haupt R, Kuehni CE, Kremer LC, de Vathaire F, Hjorth L, Reulen RC. Risk of subsequent gliomas and meningiomas among 69,460 5-year survivors of childhood and adolescent cancer in Europe: the PanCareSurFup study. Br J Cancer. 2024 Apr;130(6):976-986. doi: 10.1038/s41416-024-02577-y. Epub 2024 Jan 19. PMID: 38243010; PMCID: PMC10951281.
- Gunnes MW, Benneche A, Bechensteen AG. Et barn med langvarig anemi. Tidsskr Nor Laegeforen. 2024 Mar 15;144(4). Norwegian. doi: 10.4045/tidsskr.23.0415. PMID: 38506013.
- Heymer EJ, Jóźwiak K, Kremer LC, Winter DL, de Vathaire F, Sunguc C, Sugden E, Kok JL, van der Pal HJH, Hjorth L, Jakab Z, Maule MM, Haupt R, Bagnasco F, Terenziani M, Diallo I, Gunnes MW, Sommer G, Zadravec Zaletel L, Kuehni CE, Winther JF, Lähteenmäki PM, Gudmundsdottir T, Allodji RS, Skinner R, Ronckers CM, Hawkins MM, Reulen RC, Teepen JC. Cumulative Absolute Risk of Subsequent Colorectal Cancer After Abdominopelvic Radiotherapy Among Childhood Cancer Survivors: A PanCareSurFup Study. J Clin Oncol. 2024 Jan 20;42(3):336-347. doi: 10.1200/JCO.23.00452. Epub 2023 Nov 16. PMID: 37972325.
- Peyrl A, Chocholous M, Sabel M, Lassaletta A, Sterba J, Leblond P, Nysom K, Torsvik I, Chi SN, Perwein T, Jones N, Holm S, Nyman P, Mörse H, Öberg A, Weiler-Wichtl L, Leiss U, Haberler C, Schmook MT, Mayr L, Dieckmann K, Kool M, Gojo J, Azizi AA, André N, Kieran M, Slavc I. Sustained Survival Benefit in Recurrent Medulloblastoma by a Metronomic Antiangiogenic Regimen: A Nonrandomized Controlled Trial. JAMA Oncol. 2023 Oct 26:e234437. doi: 10.1001/jamaoncol.2023.4437. Epub ahead of print. PMID: 37883081; PMCID: PMC10603581.
- Bratteteig M, Rueegg CS, Raastad T, Grydeland M, Torsvik IK, Schindera C, Ruud E, Anderssen SA. Physical Activity, Fitness, and Cardiovascular Disease Risk in Adolescent Childhood Cancer Survivors Compared to Controls: The Physical Activity in Childhood Cancer Survivors Study. J Adolesc Young Adult Oncol. 2023 Sep 13. doi: 10.1089/jayao.2023.0063. Epub ahead of print. PMID: 37703544.
- Grydeland M, Bratteteig M, Rueegg CS, Lie HC, Thorsen L, Larsen EH, Brügmann-Pieper S, Torsvik IK, Götte M, Lähteenmäki PM, Kriemler S, Fridh MK, Anderssen SA, Ruud E. Physical Activity Among Adolescent Cancer Survivors: The PACCS Study. Pediatrics. 2023 Sep 1;152(3):e2023061778. doi: 10.1542/peds.2023-061778. PMID: 37646086.
- Andries A, Ørstavik K, Rueegg CS, Eng S, Edvardsen E, Allen SM, Torsvik IK, Raastad T, Ruud E, Nilsen KB. Polyneuropathy in Adolescent Childhood Cancer Survivors: The PACCS Study. Pediatr Neurol. 2023 Mar;140:9-17. doi: 10.1016/j.pediatrneurol.2022.11.012. Epub 2022 Nov 25. PMID: 36586183.
- Dudley IM, Sunguc C, Heymer EJ, Winter DL, Teepen JC, Belle FN, Bárdi E, Bagnasco F, Gudmundsdottir T, Skinner R, Michel G, Byrne J, Øfstaas H, Jankovic M, Mazić MČ, Mader L, Loonen J, Garwicz S, Wiebe T, Alessi D, Allodji RS, Haddy N, Grabow D, Kaatsch P, Kaiser M, Maule MM, Jakab Z, Gunnes MW, Terenziani M, Zaletel LZ, Kuehni CE, Haupt R, de Vathaire F, Kremer LC, Lähteenmäki PM, Winther JF, Hjorth L, Hawkins MM, Reulen RC. Risk of subsequent primary lymphoma in a cohort of 69,460 five-year survivors of childhood and adolescent cancer in Europe: The PanCareSurFup study. Cancer. 2023 Feb 1;129(3):426-440. doi: 10.1002/cncr.34561. Epub 2022 Nov 29. PMID: 36444554; PMCID: PMC10099796.
- Sunguc C, Hawkins MM, Winter DL, Dudley IM, Heymer EJ, Teepen JC, Allodji RS, Belle FN, Bagnasco F, Byrne J, Bárdi E, Ronckers CM, Haddy N, Gudmundsdottir T, Garwicz S, Jankovic M, van der Pal HJH, Mazić MČ, Schindera C, Grabow D, Maule MM, Kaatsch P, Kaiser M, Fresneau B, Michel G, Skinner R, Wiebe T, Sacerdote C, Jakab Z, Gunnes MW, Terenziani M, Winther JF, Lähteenmäki PM, Zaletel LZ, Kuehni CE, Kremer LC, Haupt R, de Vathaire F, Hjorth L, Reulen RC. Risk of subsequent primary oral cancer in a cohort of 69,460 5-year survivors of childhood and adolescent cancer in Europe: the PanCareSurFup study. Br J Cancer. 2023 Jan;128(1):80-90. doi: 10.1038/s41416-022-02016-w. Epub 2022 Nov 1. PMID: 36319851; PMCID: PMC9814398.
- Bratteteig M, Anderssen SA, Rueegg CS, Ruud E, Torsvik IK, Kriemler S, Grydeland M. Device-measured physical activity and cardiovascular disease risk in adolescent childhood cancer survivors. A physical activity in childhood cancer survivors (PACCS) study. Front Pediatr. 2022 Aug 25;10:977365. doi: 10.3389/fped.2022.977365. PMID: 36090557; PMCID: PMC9453306.
- Hermansen JU, Wojcik DM, Robinson N, Pahnke J, Haugland HK, Jamtøy AH, Flaegstad T, Halvorsen H, Lund B, Baumbusch LO, Munthe-Kaas MC. The Norwegian childhood cancer biobank. Cancer Rep (Hoboken). 2022 Aug;5(8):e1555. doi: 10.1002/cnr2.1555. Epub 2021 Sep 20. PMID: 34541832; PMCID: PMC9351664.
- Grønbæk JK, Laustsen AF, Toescu S, Pizer B, Mallucci C, Aquilina K, Molinari E, Hjort MA, Gumbeleviciene L, Hauser P, Pálmafy B, van Baarsen K, Hoving E, Zipfel J, Ehrstedt C, Grillner P, Callesen MT, Frič R, Wibroe M, Nysom K, Schmiegelow K, Sehested A, Mathiasen R, Juhler M; CMS study group. Left-handedness should not be overrated as a risk factor for postoperative speech impairment in children after posterior fossa tumour surgery: a prospective European multicentre study. Childs Nerv Syst. 2022 Aug;38(8):1479-1485. doi: 10.1007/s00381-022-05567-8. Epub 2022 Jun 27. PMID: 35759029.
- Lie HC, Anderssen S, Rueegg CS, Raastad T, Grydeland M, Thorsen L, Stensrud T, Edvardsen E, Larsen MH, Torsvik IK, Bovim LP, Götte M, Lähteenmäki PM, Kriemler S, Larsen HB, Fridh MK, Ørstavik K, Brun H, Matthews I, Hornset E, Ruud E. The Physical Activity and Fitness in Childhood Cancer Survivors (PACCS) Study: Protocol for an International Mixed Methods Study. JMIR Res Protoc. 2022 Mar 8;11(3):e35838. doi: 10.2196/35838. PMID: 35258456; PMCID: PMC8941432.
- Grønbæk JK, Wibroe M, Toescu S, Frič R, Thomsen BL, Møller LN, Grillner P, Gustavsson B, Mallucci C, Aquilina K, Fellows GA, Molinari E, Hjort MA, Westerholm-Ormio M, Kiudeliene R, Mudra K, Hauser P, van Baarsen K, Hoving E, Zipfel J, Nysom K, Schmiegelow K, Sehested A, Juhler M, Mathiasen R; CMS study group. Postoperative speech impairment and surgical approach to posterior fossa tumours in children: a prospective European multicentre cohort study. Lancet Child Adolesc Health. 2021 Nov;5(11):814-824. doi: 10.1016/S2352-4642(21)00274-1. Epub 2021 Oct 6. PMID: 34624241.
- Thastrup M, Marquart HV, Levinsen M, Modvig S, Abrahamsson J, Albertsen BK, Frost BM, Harila-Saari A, Pesola J, Ulvmoen A, Wojcik DM, Taskinen M, Hoffmann M, Lausen B, Schmiegelow K; Nordic Society of Paediatric Haematology, Oncology (NOPHO). Flow cytometric analysis of cerebrospinal fluid improves detection of leukaemic blasts in infants with acute lymphoblastic leukaemia. Br J Haematol. 2021 Oct;195(1):119-122. doi: 10.1111/bjh.17769. Epub 2021 Aug 15. PMID: 34396501.
- Brenner AK, Gunnes MW. Therapeutic Targeting of the Anaplastic Lymphoma Kinase (ALK) in Neuroblastoma-A Comprehensive Update. Pharmaceutics. 2021 Sep 8;13(9):1427. doi: 10.3390/pharmaceutics13091427. PMID: 34575503; PMCID: PMC8470592.
- Stensvold E, Myklebust TÅ, Cappelen J, Due-Tønnessen BJ, Due-Tønnessen P, Kepka A, Johannesen TB, Krossnes B, Lundar T, Maric S, Miletic H, Moholdt V, Myrmel KS, Nordberg T, Rydland J, Stokland T, Solem K, Solheim O, Torsvik I, Wikran GC, Zeller B, Wesenberg F, Bechensteen AG, Brandal P. Children treated for medulloblastoma and supratentorial primitive neuroectodermal tumor in Norway from 1974 through 2013: Unexplainable regional differences in survival. Pediatr Blood Cancer. 2019 Oct;66(10):e27910. doi: 10.1002/pbc.27910. Epub 2019 Jul 1. PMID: 31264356.
- El-Khouly FE, Veldhuijzen van Zanten SEM, Santa-Maria Lopez V, Hendrikse NH, Kaspers GJL, Loizos G, Sumerauer D, Nysom K, Pruunsild K, Pentikainen V, Thorarinsdottir HK, Rutkauskiene G, Calvagna V, Drogosiewicz M, Dragomir M, Deak L, Kitanovski L, von Bueren AO, Kebudi R, Slavc I, Jacobs S, Jadrijevic-Cvrlje F, Entz-Werle N, Grill J, Kattamis A, Hauser P, Pears J, Biassoni V, Massimino M, Lopez Aguilar E, Torsvik IK, Joao Gil-da-Costa M, Kumirova E, Cruz-Martinez O, Holm S, Bailey S, Hayden T, Thomale UW, Janssens GOR, Kramm CM, van Vuurden DG. Diagnostics and treatment of diffuse intrinsic pontine glioma: where do we stand? J Neurooncol. 2019 Oct;145(1):177-184. doi: 10.1007/s11060-019-03287-9. Epub 2019 Sep 14. PMID: 31522324; PMCID: PMC6775536.
- Kvistad SAS, Gunnes MW, Hagen KG, Berentsen S. A three year-old boy with back pain, fever and cola-coloured urine. Tidsskr Nor Laegeforen. 2019 Mar 18;139(6). English, Norwegian. doi: 10.4045/tidsskr.18.0532. PMID: 30917633.
- Veldhuijzen van Zanten SEM, Baugh J, Chaney B, De Jongh D, Sanchez Aliaga E, Barkhof F, Noltes J, De Wolf R, Van Dijk J, Cannarozzo A, Damen-Korbijn CM, Lieverst JA, Colditz N, Hoffmann M, Warmuth-Metz M, Bison B, Jones DTW, Sturm D, Gielen GH, Jones C, Hulleman E, Calmon R, Castel D, Varlet P, Giraud G, Slavc I, Van Gool S, Jacobs S, Jadrijevic-Cvrlje F, Sumerauer D, Nysom K, Pentikainen V, Kivivuori SM, Leblond P, Entz-Werle N, von Bueren AO, Kattamis A, Hargrave DR, Hauser P, Garami M, Thorarinsdottir HK, Pears J, Gandola L, Rutkauskiene G, Janssens GO, Torsvik IK, Perek-Polnik M, Gil-da-Costa MJ, Zheludkova O, Shats L, Deak L, Kitanovski L, Cruz O, Morales La Madrid A, Holm S, Gerber N, Kebudi R, Grundy R, Lopez-Aguilar E, Zapata-Tarres M, Emmerik J, Hayden T, Bailey S, Biassoni V, Massimino M, Grill J, Vandertop WP, Kaspers GJL, Fouladi M, Kramm CM, van Vuurden DG; members of the SIOPE DIPG Network. Development of the SIOPE DIPG network, registry and imaging repository: a collaborative effort to optimize research into a rare and lethal disease. J Neurooncol. 2017 Apr;132(2):255-266. doi: 10.1007/s11060-016-2363-y. Epub 2017 Jan 21. PMID: 28110411; PMCID: PMC5378734.
- Gunnes MW, Lie RT, Bjørge T, Ghaderi S, Syse A, Ruud E, Wesenberg F, Moster D. Suicide and violent deaths in survivors of cancer in childhood, adolescence and young adulthood-A national cohort study. Int J Cancer. 2017 Feb 1;140(3):575-580. doi: 10.1002/ijc.30474. Epub 2016 Oct 26. PMID: 27750385.
- Gunnes MW, Lie RT, Bjørge T, Syse A, Ruud E, Wesenberg F, Moster D. Economic independence in survivors of cancer diagnosed at a young age: A Norwegian national cohort study. Cancer. 2016 Dec 15;122(24):3873-3882. doi: 10.1002/cncr.30253. Epub 2016 Aug 12. PMID: 27518040; PMCID: PMC5157778.
- Veldhuijzen van Zanten SE, van Meerwijk CL, Jansen MH, Twisk JW, Anderson AK, Coombes L, Breen M, Hargrave OJ, Hemsley J, Craig F, Cruz O, Kaspers GJ, van Vuurden DG, Hargrave DR; SIOPE DIPG Network. Palliative and end-of-life care for children with diffuse intrinsic pontine glioma: results from a London cohort study and international survey. Neuro Oncol. 2016 Apr;18(4):582-8. doi: 10.1093/neuonc/nov250. Epub 2015 Oct 11. PMID: 26459800; PMCID: PMC4799684.
- Mjelle AB, Donner EM, Berg A. Et barn med kramper og plutselig synstap under cellegiftbehandling [A child with cramps and sudden vision loss during chemotherapy]. Tidsskr Nor Laegeforen. 2015 Mar 10;135(5):441-4. Norwegian. doi: 10.4045/tidsskr.13.1486. PMID: 25761031.
- Tuckuviene R, Ranta S, Albertsen BK, Andersson NG, Bendtsen MD, Frisk T, Gunnes MW, Helgestad J, Heyman MM, Jonsson OG, Mäkipernaa A, Pruunsild K, Tedgård U, Trakymiene SS, Ruud E. Prospective study of thromboembolism in 1038 children with acute lymphoblastic leukemia: a Nordic Society of Pediatric Hematology and Oncology (NOPHO) study. J Thromb Haemost. 2016 Mar;14(3):485-94. doi: 10.1111/jth.13236. Epub 2016 Jan 30. PMID: 26707629.
- Ghaderi S, Engeland A, Gunnes MW, Moster D, Ruud E, Syse A, Wesenberg F, Bjørge T. Educational attainment among long-term survivors of cancer in childhood and adolescence: a Norwegian population-based cohort study. J Cancer Surviv. 2016 Feb;10(1):87-95. doi: 10.1007/s11764-015-0453-z. Epub 2015 May 1. PMID: 25929213.
- Ghaderi S, Engeland A, Moster D, Ruud E, Syse A, Wesenberg F, Bjørge T. Increased uptake of social security benefits among long-term survivors of cancer in childhood, adolescence and young adulthood: a Norwegian population-based cohort study. Br J Cancer. 2013 Apr 16;108(7):1525-33. doi: 10.1038/bjc.2013.107. Epub 2013 Mar 12. PMID: 23481179; PMCID: PMC3629421.
- Ghaderi S, Lie RT, Moster D, Ruud E, Syse A, Wesenberg F, Bjørge T. Cancer in childhood, adolescence, and young adults: a population-based study of changes in risk of cancer death during four decades in Norway. Cancer Causes Control. 2012 Aug;23(8):1297-305. doi: 10.1007/s10552-012-0007-x. Epub 2012 Jun 17. Erratum in: Cancer Causes Control. 2013 Dec;24(12):2253-6. PMID: 22706693.
- Hirth A, Pedersen PH, Wester K, Mörk S, Helgestad J. Cerebral atypical teratoid/rhabdoid tumor of infancy: long-term survival after multimodal treatment, also including triple intrathecal chemotherapy and gamma knife radiosurgery--case report. Pediatr Hematol Oncol. 2003 Jun;20(4):327-32. PMID: 12746165.
- Hirth A, Pedersen PH, Baardsen R, Larsen JL, Krossnes BK, Helgestad J. Gamma-knife radiosurgery in pediatric cerebral and skull base tumors. Med Pediatr Oncol. 2003 Feb;40(2):99-103. doi: 10.1002/mpo.10218. PMID: 12461793.
12.06.2024