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The Department of Biomedicine

News archive for The Department of Biomedicine

Structure of actin, profilin and NAA80
Mechanism of a cell motility regulator (07.04.2020)
Actin is the most abundant protein in human cells and is involved in numerous functions including steering cellular architecture, cell motility and cell division. Recently, UiB researchers identified NAA80 as a long-sought actin regulator. Now, the structure of NAA80 bound to actin and profilin reveals its mechanism of action.
Research_Exosomes_results
Exosome-derived miRNAs in the pre-metastatic niche formation in melanoma brain metastases (02.04.2020)
Exosomes released from the primary tumour into circulation have been documented to promote pre-metastatic niche formation. We have identified a miRNA in exosomes from melanoma brain metastases that can play a vital role in this process. Knock-down (KD) of this miRNA results in an inhibition of brain metastatic growth. We are in the process of identifying potential drugs inhibiting the expression... Read more
Research Collaboration with Suzhou Institute for Brainsmatics
Studying brain tumorigenesis and brain metastasis development through high-throughput and high-resolution brain mapping (02.04.2020)
Research leaders at the Translational Cancer Research group have newly established a research collaboration with the HUST-Suzhou Institute for Brainsmatics, to study the development of brain tumors and brain metastasis.