News archive for The Department of Biomedicine

CNPase is an enzyme present at high levels in myelinating cells. Novel nanobody tools developed in an international collaboration were used to identify binding epitopes at atomic resolution and visualise myelin. Additionally, the nanobodies were used as intrabodies to bind to CNPase in living cells. These nanotools will be valuable for future research on myelin and its molecules.

Congratulation to José Miguel Godoy who won the prizes for best 3-min presentation at the Biocat conference last week.

New PhD using deep learning to analyse multiparametric MRI images to grade and track tumour cell spreading in the brain.

BORTEM-17 interim analysis results and small molecule inhibitor targeting CSPG4/NG2 in glioblastoma at American Association for Cancer Research (AACR 2024) April 5-10, 2024

Tore Ivar Malmei Aarsland will defend his PhD degree at the University of Bergen on 21 May 2024 with the thesis "Tryptophan and kynurenine pathway metabolites in neuropsychiatric disorders".

Brain calcification can cause movement disorders and cognitive impairment. New research by the Arnesen Lab at UiB provides increased insight into how these calcifications occur.

The Brenk lab has co-authored a paper describing the EU-Openscreen fragment library.

The Brenk lab has published an article in which they have investigated the presence of metal-coordinating groups in screening libraries and chemical spaces. This can help with the discovery for new inhibitors for metallo enzymes.