News archive for The Department of Biomedicine

New gene variants linked to congenital heart disease (13.02.2021)

Around 600 children are born with congenital heart disease in Norway each year. Little is known about the causes of congenital heart defects. A new international study involving researchers from University of Bergen and Haukeland University Hospital shows that the NAA15 protein can play an important role.

GADL1, a novel enzyme to improve athletic performance (09.02.2021)

Carnosine plays an important roles as antioxidant, pH buffer, and neuromodulator and recently received increasing attention as biomarker for many disease states such as Alzheimer disease and Parkinson disease. The Neurotargeting group at the Department of Biomedicine discovered a novel enzyme, Glutamate Decarboxylase Like 1 (GADL1) that plays a role in carnosine production.

Invitation to submit a research article to Cancers (IF 6.13) (03.02.2021)

"Immunological, Molecular and Imaging Biomarkers of Malignant Progression in Brain Cancer: Improving Precision Neuro-Oncology"

Structures of two CMT mutation targets revealed (02.02.2021)

Charcot-Marie-Tooth disease (CMT) is the most common inherited neuropathy in humans, linked to mutations in dozens of different genes. Two of these genes encode the proteins GDAP1 and NDRG1. We have solved the crystal structures of these two proteins, in order to better understand their structure, function, and involvement in disease.