BBB Seminars - Archive 2009 - 2016

Spring 2016

• Thursday, January 14, 14.30
• BBB seminar
• Donna Marie Briggs Bødtkjer, Department of Biomedicine and Department of Clinical Medicine, Aarhus University, Denmark
• The dynamic nature of human collecting lymphatic vessels

• Thursday, January 21, 14.30
• BBB seminar
• Kristina Viktorsson, Department of Oncology-Pathology, Karolinska Institutet, Stockholm, Sweden
• Personalized cancer medicine in lung cancer – identification of novel therapeutics and associated biomarkers

• Thursday, January 28, 14.30
• CCBIO seminar
• Jean-Christophe Bourdon, Centre for Oncology and Molecular Medicine, Dundee Cancer Centre, and Jacqui Wood Cancer Centre, Ninewells Hospital, University of Dundee, UK
• A decade of research on p53 summarised

• Thursday, February 4, 14.30
• BBB seminar
• Tilo Wolf Eichler, Department of Clinical Medicine, University of Bergen
• Paraneoplastic neurological disorders: when the body damages itself in the battle against cancer

• Thursday, February 11, 14.30
• BBB seminar
• Marc Vaudel, Department of Biomedicine, University of Bergen
• Harness bioinformatics, unleash your research

• Thursday, February 18, 14.30
• BBB seminar
• Kenneth Hensley, Department of Pathology, University of Toledo, OH, USA
• Brain, heal thyself: Using natural brain amino acid metabolites to protect and repair damaged neurons

• Thursday, February 25, 14.30
• CCBIO seminar
• Olivier De Wever, Laboratory of Experimental Cancer Research, Department of Radiation Oncology and Experimental Cancer Research, Ghent University, Belgium
• Communication in the tumor environment: diagnostic and therapeutic opportunities

• Thursday, March 3, 14.30
• BBB seminar
• Eivind Valen, Computational Biology Unit, Department of Informatics, University of Bergen
• Searching for function in the dark matter of the genome

• Thursday, March 10, 14.30
• BBB seminar
• Hermes Hsiao-Mei Yeh, Department of Physiology and Neurobiology, Geisel School of Medicine at Dartmouth, Dartmouth-Hitchcock Medical Center, Lebanon, NH, USA
• Prenatal alcohol exposure, GABA, and enduring interneuronopathy in the prefrontal cortex

• Thursday, March 17, 14.30
• CCBIO seminar
• Lutz P. Müller, Department of Internal Medicine IV – Hematology and Oncology, Martin Luther University Halle-Wittenberg, Halle, Germany
• Growth promotion of colorectal cancer by mesenchymal stromal cells – when and how?

• Thursday, March 31, 14.30
• BBB seminar
• Krystof Bankiewicz, Department of Neurological Surgery, University of California San Francisco, CA, USA
• Convection enhanced delivery of nanoparticles and retroviral replicating vector into recurrent brain tumors under real-time MRI guidance

• Thursday, April 7, 14.30
• BBB seminar
• Richard Alan Engh, Department of Chemistry, University of Tromsø
• Understanding enzyme flexibility is essential for structure based protein kinase inhibitor drug discovery

• Thursday, April 14, 14.30
• BBB seminar
• J. Jay Couey, Neurobiological Psychiatry Group, Department of Psychiatry, Erasmus Medical Centre, Rotterdam, The Netherlands
• Molecular and physiological changes in Arc-defined fear memory engrams in the mouse dentate gyrus

• Thursday, April 21, 14.30
• BBB seminar
• Jaakko Saraste, Department of Biomedicine and Molecular Imaging Center, University of Bergen
• Functional symmetry of endomembranes

• Thursday, April 28, 14.30
• CCBIO seminar
• Krister Wennerberg, Institute for Molecular Medicine Finland, University of Helsinki, Finland
• Targeting cancers using individual systems medicine

• Thursday, May 12, 14.30
• BBB seminar
• Stefan Raunser, Department of Structural Biochemistry, Max Planck Institute of Molecular Physiology, Dortmund, Germany
• Molecular mechanisms explained by single particle cryo-EM

• Thursday, May 19, 14.30
• BBB seminar
• Charalampos Tzoulis, Department of Clinical Medicine, University of Bergen
• Parkinson’s disease – a journey into heredity, entropy and energy failure

• Thursday, May 26 - NB! Starting at 13.30
• CCBIO special seminar
• Anne Blanchard, CCBIO; John Torgils Vaage, Oslo University Hospital; Jim Lorens, CCBIO; Richard Godfrey, BerGenBio AS
• Pharma and public cancer biomarker research in the transition from a blockbuster model to personalised medicine

• Thursday, June 2, 14.30
• BBB seminar and Biokjemisk Kollokvium (NBS, Bergen Division)
• Christopher M. Overall, UBC Centre for Blood Research, University of British Columbia, Vancouver, BC, Canada
• Quantitative proteomics and systems biology analysis of proteolytic networks in vivo

• Thursday, June 9, 14.30
• BBB seminar
• Angel Barco, Laboratory for Transcriptional and Epigenetic Mechanisms of Neuronal Plasticity, The Instituto de Neurociencias de Alicante, Spain
• The genetics and epigenetics of intellectual disability

• Thursday, June 16, 14.30
• CCBIO seminar
• Gwendalyn Randolph, Department of Pathology and Immunology, Washington University School of Medicine, St. Louis, MO, USA
• The lymphatic vasculature in immunity and inflammatory disease

Autumn 2016

• Thursday, August 18, 14.30
• BBB seminar
• Erling Andre Høivik, Department of Clinical Science, University of Bergen
• Genomic analysis of paired endometrial cancer primaries and metastases

• Thursday, August 25, 14.30 – NB! Auditorium 2
• CCBIO seminar
• Jonathan M. Irish, Department of Cancer Biology, Vanderbilt University, Nashville, TN, USA
• Decoding human tumor microenvironments and healthy tissues using high dimensional single cell mass cytometry

• Thursday, September 1, 14.30
• BBB seminar
• Pablo García de Frutos, Department of Cell Death and Proliferation, Institute of Biomedical Research of Barcelona, Spanish National Research Council, Barcelona, Spain
• GAS6/TAM system in physiology and disease

• Thursday, September 8, 14.30
• BBB seminar
• Ilme Schlichting, Max Planck Institute for Medical Research, Heidelberg, Germany
• Protein structure and dynamics using X-ray free-electron lasers

• Thursday, September 15, 14.30
• BBB seminar, jointly with the Department of Molecular Biology
• Hans E. Krokan, Department of Cancer Research and Molecular Medicine, Norwegian University of Science and Technology (NTNU), Trondheim
• Genomic uracil – Important carcinogenic lesion, but normal intermediate in adaptive immunity

• Thursday, September 22, 14.30
• BBB seminar
• Christopher A. McCulloch, Matrix Dynamics Group, University of Toronto, ON, Canada
• Use of tandem mass tag spectrometry for identifying novel molecules in IL-1 signal transduction

• Thursday, September 29, 14.30
• CCBIO seminar
• Herbert B. Schiller, Comprehensive Pneumology Center, Helmholtz Zentrum München, Member of the German Center for Lung Research (DZL), Munich, Germany
• Multi-dimensional proteomics of the extracellular matrix in regeneration and fibrosis

• Thursday, October 6, 14.30
• BBB seminar
• Christian Aalkjær, Department of Biomedicine, Aarhus University and Department of Biomedical Sciences, University of Copenhagen, Denmark
• The remarkable cardiovascular system of giraffes

• Thursday, October 13, 14.30
• BBB seminar
• Marianne Hafting Fyhn, Department of Biosciences and Centre for Integrative Neuroplasticity (CINPLA), University of Oslo
• The role of perineuronal nets in cortical plasticity and remote memory storage

• Thursday, October 20, 14.30
• BBB seminar
• Philipp Scherer, Touchstone Diabetes Center, Department of Internal Medicine, University of Texas Southwestern Medical Center, Dallas, TX, USA
• The multifaceted roles of adipose tissue: Therapeutic targets for diabetes and beyond

• Monday, October 24, 14.30 - NB! Day and Auditorium 2
• BBB extra seminar
• Sir Philip Cohen, MRC Protein Phosphorylation and Ubiquitylation Unit, Sir James Black Centre, University of Dundee, Scotland, UK
• The role of hybrid ubiquitin chains in the regulation of innate immune signalling networks

• Thursday, October 27 – NB! Postponed
• CCBIO seminar
• Kári Stefánsson, University of Iceland and deCODE Genetics, Reykjavik, Iceland

• Thursday, November 3, 14.30 – NB! Auditorium 2
• BBB seminar
• Joerg Bewersdorf, Department of Cell Biology and Department of Biomedical Engineering, Yale University, New Haven, CT, USA
• Pushing the limits of optical nanoscopy: Imaging whole cells at sub-20-nm 3D resolution and living cells in multiple colors

• Thursday, November 10, 14.30 – NB! Auditorium 2
• CCBIO seminar
• Caroline Heckman, Institute for Molecular Medicine Finland (FIMM), University of Helsinki, Finland
• In vitro drug screens in acute myeloid leukemia

• Thursday, November 17, 14.30
• BBB seminar
• Nils Halberg, Department of Biomedicine, University of Bergen
• Tumor ecosystems: the obesity-cancer connection

• Thursday, November 24, 14.30
• BBB seminar
• Pierre Vincent, Cellular Integration of Neuromodulatory Processes, UMR8256 Biological Adaptation and Ageing, Sorbonne Universities, UPMC University Paris, France
• Monitoring the integration of cyclic nucleotide signals in neurons using biosensor imaging

• Thursday, December 1, 14.30
• CCBIO seminar
• Jean Paul Thiery, Centre for Cancer Biomarkers (CCBIO), University of Bergen, Yong Loo Lin School of Medicine, National University of Singapore, University of Paris Denis Diderot and Comprehensive Cancer Center, Institut Gustave Roussy, Villejuif, France
• Epithelial cell plasticity in carcinoma: Harnessing mechanisms controlling biomechanics and progression of malignancy for the design of new therapeutic strategies

• Thursday, December 8, 14.30
• BBB seminar
• Daniel Rauh, Department of Chemistry and Chemical Biology, TU Dortmund University, Germany
• Chemical oncology

• Thursday, December 15, 14.30
• CCBIO seminar
• Kenneth Hugdahl, Department of Biological and Medical Psychology, University of Bergen; Division of Psychiatry and Department of Radiology, Haukeland University Hospital, Bergen
• Excellence in science: Experience with ERC grants

Spring 2015

• Thursday, January 15, 14.30
• BBB seminar
• Seppo J. Vainio, Biocenter Oulu, InfoTech Oulu, Center for Cell-Matrix Research, University of Oulu, Finland
• Targeting the program that organizes the stem cells into a nephron, the functional unit of the mammalian kidney

• Thursday, January 22, 14.30
• CCBIO seminar
• John Cairns, Centre for Cancer Biomarkers, Department of Economics, University of Bergen, and Department of Health Services Research and Policy, London School of Hygiene and Tropical Medicine, UK
• Assessing the cost-effectiveness of bevacizumab in the treatment of metastatic melanoma

• Thursday, January 29, 14.30
• BBB seminar
• Harald Stenmark, Institute for Cancer Research, the Norwegian Radium Hospital, Oslo University Hospital
• How contacts between the endocytic and exocytic pathways promote neurite outgrowth

• Thursday, February 5, 14.30
• BBB seminar
• Karianne Fjeld, KG Jebsen Center for Diabetes Research, Department of Clinical Science, University of Bergen
• New insight into pancreatic disease etiology: the role of CEL in diabetes and pancreatitis

• Thursday, February 12 - No seminar

• Thursday, February 19, 14.30
• CCBIO seminar
• Anne Christine Johannessen, Centre for Cancer Biomarkers, Department of Clinical Medicine, University of Bergen
• Oral cancer – ongoing research with special focus on tumour microenvironment

• Thursday, February 26, 14.30
• BBB seminar
• Cornelia Halin, Institute of Pharmaceutical Sciences, Swiss Federal Institute of Technology, Zurich, Switzerland
• New insights into the immune and drainage functions of lymphatic vessels

• Thursday, March 5, 14.30 - NB! Histology Room no. 2, 4th floor, BBB
• BBB seminar
• Pål Stenmark, Department of Biochemistry and Biophysics, Stockholm University, Sweden
• Structural biology targeting human disease

• Thursday, March 12, 14.30
• BBB seminar
• Alexander Espinosa, Experimental Rheumatology Unit, Center for Molecular Medicine, Karolinska University Hospital, Stockholm, Sweden
• The role of IFN-regulated genes in systemic autoimmunity

• Thursday, March 19, 14.30
• BBB seminar
• Petri Kursula, Department of Biomedicine, University of Bergen
• Using protein structures to understand myelin biology and disease

• Thursday, March 26, 14.30
• CCBIO seminar
• Hani Gabra, Ovarian Cancer Action Research Centre, Department of Surgery and Cancer, Imperial College London, UK
• OPCML and the regulation of receptor tyrosine kinase network: Focus on AXL

• Thursday, April 9, 14.30
• BBB seminar
• Christos G. Gkogkas, Centre for Integrative Physiology and Patrick Wild Centre, University of Edinburgh, UK
• Regulation of neuronal translation in Autism Spectrum Disorders

• Thursday, April 16, 14.30
• BBB seminar 
• Karin Wibrand, Department of Biomedicine and KG Jebsen Centre for Research on Neuropsychiatric Disorders, University of Bergen
• Transcriptomic analysis reveals a dynamic expression of long noncoding RNAs and repeat elements in synaptic plasticity

• Thursday, April 23, 14.30
• BBB seminar
• Catherine W. Morgans, Department of Physiology and Pharmacology, Oregon Health & Science University, Portland, OR, USA
• The TRPM1 cation channel: A link between vision and skin cancer

• Thursday, April 30, 14.30
• CCBIO seminar
• Lorena Arranz, Stem Cell Aging and Cancer Research Group, Department of Medical Biology, UiT The Arctic University of Norway, Tromsø
• Neuroglial dysregulation of the haematopoietic stem cell niche in myeloid leukaemias

• Thursday, May 7, 14.30
• BBB seminar
• Clifford Kentros, Kavli Institute for Systems Neuroscience, Norwegian University of Science and Technology (NTNU), Trondheim
• Transgenic investigation of the neural circuitry of memory

• Wednesday, May 13, 13.00 - NB! Day and time
• BBB seminar and Biokjemisk Kollokvium (NBS, Bergen Division)
• Kai Simons, Max Planck Institute of Molecular Cell Biology and Genetics, Dresden, Germany
• Cell membranes: subcompartmentalization driven by phase separation

• Thursday, May 21, 14.30
• BBB seminar
• Albert Sickmann, Bioanalytics Department, Leibniz-Institut für Analytische Wissenschaften - ISAS - e.V., Dortmund, Germany
• Moving from inventory to personalized medicine: reducing cardiovascular mortality

• Thursday, May 28, 14.30
• CCBIO seminar
• Neil C. Henderson, MRC Center for Inflammation Research, The Queen's Medical Research Institute, University of Edinburgh, UK
• Targeting of pericytes and tissue myofibroblasts during organ fibrogenesis

• Thursday, June 4, 14.30
• BBB seminar
• Ulrich Valcourt, Cancer Research Center of Lyon (CRCL), French Institute of Health and Medical Research (INSERM), University of Lyon, France
• Tenascin-X promotes epithelial-to-mesenchymal transition by activating latent TGF-β

• Thursday, June 11, 14.30
• BBB & CCBIO seminar
• Robert S. Kerbel, Biological Sciences Platform, Sunnybrook Research Institute, Toronto, and Department of Medical Biophysics, University of Toronto, Canada
• Antiangiogenic therapeutics in oncology: Overview, update, and future directions

• Monday, June 15, 14.30 - NB! Day
• BBB seminar
• Matti S. Airaksinen, Department of Anatomy, Institute of Biomedicine, University of Helsinki, Finland
• LRRTM family of synaptic cell adhesion proteins

Autumn 2015

• Thursday, August 20, 14.30
• BBB seminar
• Rolf Bjerkvig, Department of Biomedicine and K.G. Jebsen Brain Tumour Research Centre, University of Bergen
• Malignant brain tumours: Their initiation and progression and resistance mechanisms to anti-angiogenic therapy

• Thursday, August 27, 14.30
• CCBIO seminar
• Roya Navab, Princess Margaret Cancer Centre, University Health Network, Toronto, ON, Canada
• Integrin α11β1 regulates cancer stromal stiffness and promotes tumorigenicity and metastasis in non-small cell lung cancer

• Thursday, September 3, 14.30
• BBB seminar
• Jason Matthews, Department of Nutrition, Institute of Basic Medical Sciences, University of Oslo
• TIPARP and ADP-ribosylation regulate aryl hydrocarbon receptor activity and dioxin-induced steatohepatitis and lethality

• Thursday, September 10, 14.30
• BBB seminar
• Stefan Rose-John, Department of Biochemistry, University of Kiel, Germany
• The biology of Interleukin-6 and strategies of therapeutic blockade

• Thursday, September 17, 14.30
• BBB seminar
• Bodour Salhia, Integrated Cancer Genomics Division, Translational Genomics Research Institute, Phoenix, AZ, USA
• Development of better predictive, preventative and curative treatments for metastatic breast cancer

• Thursday, September 24, 14.30
• CCBIO seminar
• Bruce Baguley, Auckland Cancer Society Research Centre, University of Auckland, New Zealand
• The importance of being... a receptor tyrosine kinase

• Thursday, October 1 - Cancelled
• BBB seminar
• Donna Briggs Bødtkjer, Department of Biomedicine, Aarhus University, Denmark

• Thursday, October 8, 14.30
• BBB seminar and Biokjemisk Kollokvium (NBS, Bergen Division)
• Raymond C. Stevens, Departments of Biological Sciences and Chemistry, Bridge Institute, University of Southern California, Los Angeles, CA, USA
• The incredible diversity of G-protein coupled receptors

• Thursday, October 15, 14.30
• BBB & CCBIO seminar
• Matthew G. Krebs, Institute of Cancer Sciences, University of Manchester, UK
• Circulating biomarkers in early phase drug development for lung cancer

• Thursday, October 22, 14.30 - NB! Auditorium 1
• CCBIO seminar
• Erik Sahai, Tumour Cell Biology Laboratory, London Research Institute, Cancer Research UK, London, UK
• Intravital imaging reveals how stroma dictates heterogeneous responses to targeted therapy

• Friday, October 23, 12.00 - NB! Day and time
• BBB extra seminar
• Marcel Dinger, Genomics and Epigenetics Division, Garvan Institute of Medical Research and St Vincent's Clinical School, University of New South Wales, Sydney, NSW, Australia
• Journeys through space and time: Ultra high-resolution expression profiling of long noncoding RNAs

• Thursday, October 29, 14.30
• BBB seminar
• Inari Kursula, Department of Biomedicine, University of Bergen and Faculty of Biochemistry and Molecular Medicine, University of Oulu, Finland
• Illuminating the malaria parasite gliding motor using hybrid structural biology

• Thursday, November 5, 14.30
• BBB seminar
• Ruth Brenk, Department of Biomedicine, University of Bergen
• Using crystal structures for ligand design – Druggability predictions, riboswitches and kinases

• Thursday, November 12, 14.30
• BBB seminar
• Uwe Himmelreich, Biomedical MRI Unit, Department of Imaging and Pathology, University of Leuven, Belgium
• In vivo monitoring of cell therapy – what contributions can imaging methods make in preclinical research?

• Thursday, November 19, 14.30
• BBB seminar
• Stefan Koelsch, Department of Biological and Medical Psychology, University of Bergen
• Human cardiac biomarkers of personality, disorders, and diseases

• Thursday, November 26, 14.30
• CCBIO seminar
• Patrick Schöffski, Department of General Medical Oncology, University Hospitals Leuven, Leuven Cancer Institute and Laboratory of Experimental Oncology, Department of Oncology, KU Leuven, Belgium
• Modelling mesenchymal malignancies: development of patient-derived xenografts of soft tissue sarcomas and gastrointestinal stromal tumours and in vivo-drug testing with direct implications for clinical research (bedside to bench and back)

• Thursday, December 3, 14.30
• BBB seminar
• Ilpo Vattulainen, Department of Physics, Tampere University of Technology and Department of Physics, University of Helsinki, Finland
• Tiny but tough, cholesterol! How membranes sense changes in cholesterol structure

• Thursday, December 10, 14.30
• BBB seminar
• Camilla Krakstad, Department of Biomedicine, University of Bergen, and Department of Gynecology and Obstetrics, Haukeland University Hospital, Bergen
• Improved treatment of endometrial cancer

• Thursday, December 17, 14.30
• CCBIO seminar
• Jarle Breivik, Department of Behavioural Sciences in Medicine, Institute of Basic Medical Sciences, University of Oslo
• Cancer and aging: Facing realities and an uncertain future

Spring 2014

• Thursday, January 16, 14.30
• BBB seminar
• Arvid Lundervold, Department of Biomedicine, University of Bergen 
• My sabbatical year 2013: Image analysis in space and time

• Thursday, January 23, 14.30
• BBB seminar
• Christel Herold-Mende, Division of Experimental Neurosurgery, Department of Neurosurgery, University of Heidelberg, Germany
• Glioma and immunotherapy: from bench to bedside

• Thursday, January 30, 14.30
• CCBIO seminar
• Karl-Henning Kalland, Centre for Cancer Biomarkers (CCBIO), Department of Clinical Science, University of Bergen
• Heterogeneity and reprogramming plasticity of cancer cells - therapeutic possibilities

• Thursday, February 6, 14.30
• BBB seminar
• Grethe S. Foss, formerly at Bioteknologinemnda (the Norwegian Biotechnology Advisory Board), Oslo
• The Biotechnology Act – Regulating the application of biotechnology in human medicine

• Thursday, February 13, 14.30
• BBB seminar
• Lars Skjærven, Department of Biomedicine, University of Bergen
• Bringing structural biology data to life with computer simulations – research and experiences from EMBL

• Thursday, February 20, 14.30
• CCBIO seminar
• Roger Strand, Centre for Cancer Biomarkers (CCBIO) and Centre for the Study of the Sciences and the Humanities (SVT), University of Bergen
• Crossing the Styx

• Thursday, February 27 - No seminar

• Thursday, March 6, 14.30 - NB! Auditorium 2
• BBB seminar
• Maximiliano L. Suster, Neural Circuits and Behaviour Group, Uni Research AS, Bergen
• Human-specific loss of GLRA4 reveals specialized roles of inhibitory glycine receptors in vertebrate startle and motility

• Thursday, March 13, 14.30
• BBB seminar
• Jorge Lira Ruas, Karolinska Institutet, Department of Physiology and Pharmacology, Molecular and Cellular Exercise Physiology Group, Stockholm, Sweden
• The PGC-1alpha coactivator system: Regulators of skeletal muscle function and beyond

• Thursday, March 20, 14.30
• CCBIO seminar
• Cédric Gaggioli, Institute for Research on Cancer and Aging (IRCAN), Nice, France
• Production of LIF cytokine by cancer cells and fibroblasts contributes to the establishment of a pro-invasive tumor microenvironment

• Thursday, March 27, 14.30
• BBB seminar
• Hans-Peter Marti, Department of Clinical Medicine, Haukeland University Hospital, University of Bergen
• Where do we need biomarkers in kidney diseases?

• Monday, April 7, 14.30 - NB! Day change
• BBB seminar
• Chiara Cirelli and Guilio Tononi, Department of Psychiatry, University of Wisconsin, Madison, WI, USA
• Sleep and synaptic homeostasis

• Thursday, April 10, 14.30
• BBB seminar
• George Uhl, Molecular Neurobiology Research Branch, National Institute on Drug Abuse, Intramural Research Program, NIH, Baltimore, MD, USA
• “Cell adhesion” molecules, the brain and brain disorders: examples from addiction studies

• Thursday, April 24, 14.30
• CCBIO seminar
• Angela Nieto, Developmental Neurobiology Unit, Instituto de Neurociencias CSIC-UMH, San Juan de Alicante, Spain
• Epithelial plasticity in development and disease

• Thursday, May 08, 14.30
• BBB seminar
• Hrvoje Miletic, Department of Biomedicine, University of Bergen
• Role of EGFRs in glioblastoma invasion and angiogenesis

• Thursday, May 15 - No seminar

• Thursday, May 22, 14.30
• CCBIO seminar
• Emmet McCormack, Department of Clinical Science, University of Bergen
• Pharmacological inhibition of the SIRT1 deacetylase with the small molecule inhibitor Tenovin-6 enhances ablation of FLT3-ITD+ LSC in combination with TKI treatment

• Thursday, June 5, 14.30
• BBB seminar
• Kishore Bhakoo, Translational Molecular Imaging Group, Singapore Bioimaging Consortium, Agency for Science, Technology and Research (A*STAR), Singapore
• Use of molecular imaging in stem cell clinical translation

• Thursday, June 12, 14.30
• BBB seminar
• Friedrich C. Luft, Max-Delbrück-Center for Molecular Medicine, Berlin, Germany
• How ignorance drives science

• Thursday, June 19, 14.30
• CCBIO seminar
• Guttorm Haraldsen, K.G. Jebsen Inflammation Research Centre, Oslo University Hospital, and Institute of Clinical Medicine, University of Oslo
• Vascular endothelial cells in quiescence and activation

Autumn 2014

• Thursday, August 28, 14.30
• CCBIO seminar
• Inge Jonassen, Centre for Cancer Biomarkers (CCBIO) and Computational Biology Unit, Department of Informatics, University of Bergen 
• Towards characterizing tumour microenvironments – experimental and computational approaches

• Thursday, September 4, 14.30
• BBB seminar
• Fitz-Roy Curry, Department of Physiology and Membrane Biology, School of Medicine, University of California at Davis, CA, USA
• Investigations of vascular permeability: From molecular mechanisms to functional vascular exchange

• Thursday, September 11, 14.30
• BBB seminar
• Dean Sheppard, Lung Biology Center and Department of Medicine,
  University of California San Francisco (UCSF), CA, USA
• Targeting integrin-mediated TGFβ activation to treat asthma, multiple sclerosis, acute lung injury and organ fibrosis

• Thursday, September 18, 14.30
• BBB seminar
• Colin Clyne, Cancer Drug Discovery Laboratory, Prince Henry's Institute of Medical Research, Clayton, Victoria, Australia
• Targeting orphan nuclear receptors in breast cancer

• Thursday, September 25, 14.30
• BBB seminar
• Börje Haraldsson, Department of Clinical and Molecular Medicine (Nephrology), Sahlgrenska Academy, Gothenburg University, Sweden
• Current understanding of kidney disease opens new therapeutic avenues

• Thursday, October 2, 14.30
• BBB & CCBIO seminar
• Zena Werb, Department of Anatomy, and Helen Diller Family Comprehensive Cancer Center, University of California, San Francisco, CA, USA
• New insights into mechanisms underlying breast cancer metastasis

• Thursday, October 9, 14.30
• BBB seminar
• Tõnis Timmusk, Department of Gene Technology, Tallinn University of 
  Technology, Estonia
• Regulation of the neurotrophin BDNF gene expression by neuronal activity

• Thursday, October 16, 14.30
• BBB seminar
• Michael Detmar, Institute of Pharmaceutical Sciences, ETH Zurich, Switzerland
• An important role of lymphatic vessels in cancer progression and inflammation

• Thursday, October 23, 14.30
• BBB seminar
• Jens Waschke, Institute of Anatomy and Cell Biology, Ludwig-Maximilians-University Munich, Germany
• Adherens junctions and desmosomes-roles for endothelial/epithelial integrity and barrier function

• Thursday, October 30, 14.30
• CCBIO seminar
• Boris Hinz, Laboratory of Tissue Repair and Regeneration, Matrix Dynamics Group, University of Toronto, Canada
• Myofibroblasts can have it all: matrix mechanics, integrins, and pro-fibrotic growth factor activation

• Thursday, November 6, 14.30
• BBB seminar
• Ole M. Sejersted, Institute for Experimental Medical Research, Oslo
  University Hospital and University of Oslo
• Heart failure is closely linked to deranged ultrastructure of cardiac myocytes

• Thursday, November 13, 14.30
• BBB seminar
• Sharon A. Tooze, Secretory Pathways Laboratory, London Research 
  Institute, Cancer Research UK
• Molecular mechanisms of mammalian autophagy

• Thursday, November 20, 14.30
• BBB seminar
• Brynjar Foss, Department of Health Studies, University of Stavanger
• E-learning in higher education, why & how?

• Thursday, November 27 - NB! 13.00
• CCBIO seminar
• Bjørn Tore Gjertsen, Centre for Cancer Biomarkers (CCBIO) and Translational Hemato-Oncology Group, Department of Clinical Science, University of Bergen, and Clinical Trials Unit, R&D Department, Helse Bergen
• Oncogene-addicted cancer: chronic myelogen leukemia as a model of a tyrosine kinase driven malignancy

• Thursday, December 4, 14.30
• BBB seminar
• Sakari Kellokumpu, Department of Biochemistry, University of Oulu, Finland
• Glycosyltransferase complexes: a new view to glycosylation and cancer-associated glycosylation abnormalities

• Thursday, December 11, 14.30
• BBB seminar
• Jeanette Hellgren Kotaleski, Department of Computational Biology, School of Computer Science and Communication, KTH Royal Institute of Technology, Stockholm, Sweden
• Modeling of the basal ganglia at multiple scales

• Thursday, December 18, 14.30
• CCBIO seminar
• Arne Östman, Department of Oncology-Pathology, Karolinska Institutet,
  Stockholm, Sweden
• Impact of PDGFR-regulated fibroblasts and pericytes on tumor progression, prognosis and drug response

Spring 2013

• Thursday, January 17, 13.00
• Donald Gullberg, Department of Biomedicine, University of Bergen
• My sabbatical year: muscling in on integrins 

• Thursday, January 24, 13.00
• Ross C. Walker, San Diego Supercomputer Center & Department of Chemistry and Biochemistry, University of California San Diego, La Jolla, CA, USA
• Identifying novel drug targets with advanced molecular dynamics simulations: Application to adenovirus proteases

• Thursday, January 31, 13.00
• Birgitta Åsjø, Section for Microbiology and Immunology, The Gade Institute, University of Bergen
• A 30 year involvement in HIV research

• Thursday, February 7, 13.00
• Rodrigue Rossignol, Laboratory of Rare Diseases: Genetics and Metabolism (MRGM), University of Bordeaux, France
• Mitoplasticity: Adaptation biology of the mitochondrion to the cellular redox state in physiology and carcinogenesis

• Thursday, February 14, 13.00
• Claudia Bagni, VIB Center for the Biology of Disease, University of Leuven, Belgium
• Molecular plasticity in the context of the Fragile X Syndrome

• Thursday, February 21, 13.00
• Kristiina Kompus, Department of Biological and Medical Psychology, University of Bergen
• Neural mechanisms of auditory hallucinations

• Thursday, February 28 - Cancelled
• Gilbert Weidinger, Institute for Biochemistry and Molecular Biology, Ulm University, Germany

• Thursday, March 7, 13.00
• Arne O. Smalås, Norwegian Structural Biology Center, Department of Chemistry, University of Tromsø
• Research activities at the Norwegian Structural Biology Centre (NorStruct)

• Thursday, March 14, 13.00
• Frits Alan Thorsen, Department of Biomedicine, University of Bergen 
• My sabbatical year 2011-2012: Animal models to study brain metastasis

• Thursday, March 21, 13.00
• James Lorens, Department of Biomedicine, University of Bergen
• Stem cells, EMT and cancer: The role of the Axl receptor

• Thursday, April 4, 13.00
• Carien M. Niessen, Department of Dermatology, University of Cologne, Germany 
• Regulation of cell and tissue architecture in epidermal morphogenesis and homeostasis

• Thursday, April 11, 13.00
• Agnès Noël, Laboratory of Tumor and Development Biology, Groupe Interdisciplinaire de Génoprotéomique Appliquée (GIGA-Cancer), University of Liège, Belgium
• Contribution of cancer associated fibroblasts and lymphatic endothelial cells in the remodelling of a collagen-rich tumor microenvironment

• Thursday, April 18, 13.00
• Bertil B. Fredholm, Department of Physiology and Pharmacology, Karolinska Institutet, Stockholm, Sweden
• Caffeine, adenosine and the brain

• Thursday, April 25, 13.00
• Catherine Merry, Stem Cell Glycobiology Group, Materials Science Centre, University of Manchester, UK
• Sugar-coated webs to drive stem cell differentiation

• Thursday, May 2, 13.00
• Dontscho Kerjaschki, Clinical Institute of Pathology, Medical University of Vienna, Austria
• The sunrise of understanding lymphatic vessel function in human diseases

• Thursday, May 16, 13.00 - NB! Auditorium 2
• Ian Wilmut, MRC Centre for Regenerative Medicine, University of Edinburgh, UK
• From Dolly to treatment of human disease

• Thursday, May 23, 13.00
• Karin U. Schallreuter, Centre for Skin Sciences, University of Bradford, UK
• From the bench to the bedside – In vivo and in vitro evidence for ROS/RNS-mediated stress in vitiligo

• Thursday, May 30, 13.00
• Angela M. Gronenborn, Department of Structural Biology and Pittsburgh Center for HIV Protein Interactions, University of Pittsburgh School of Medicine, PA, USA
• Novel findings for HIV capsid function - Synergy between NMR, cryo-EM and large-scale MD simulations

• Thursday, June 6, 13.00
• Robert J. Harvey, Department of Pharmacology, UCL School of Pharmacy, London, UK
• Dysfunction of inhibitory glycinergic synapses in startle disease

• Thursday, June 13, 13.00
• Kathrine Skarstein, Section for Pathology, Department of Clinical Science, University of Bergen
• Long-lived plasma cells and their survival niches in Sjögren's syndrome

• NB! Tuesday, June 18, 13.00
• Roland Jacobs, Department of Clinical Immunology and Rheumatology, Hannover Medical University, Germany
• Suppression of NK cell effector functions by umbilical-cord derived mesenchymal stem cells

Autumn 2013

• Thursday, August 22, 13.00
• Florian Krammer, Department of Microbiology, Icahn School of Medicine at Mount Sinai, New York, NY, USA
• Catching a moving target: broadly neutralizing antibodies and the development of a universal influenza virus vaccine

• Thursday, August 29, 14.30
• CCBIO Lecture
• Lars A. Akslen, Department of Clinical Medicine, University of Bergen
• CCBIO: Current concepts and challenges in cancer research

• Thursday, September 5, 14.30
• Waldemar Priebe, Department of Experimental Therapeutics, The University of Texas MD Anderson Cancer Center, Houston, TX, USA
• Drug discovery in academia: Integrating basic science and translational research

• Thursday, September 12, 14.30
• Ole Didrik Lærum, The Finsen Laboratory, Rigshospitalet, and Biotech Research & Innovation Center (BRIC), University of Copenhagen, Denmark, and Department of Clinical Medicine, University of Bergen
• Plasminogen activation and invasion of adenocarcinomas in the gastrointestinal tract

• Thursday, September 19, 8.30 - 17.30
• Preclinical Institutes / Department of Biomedicine, 50 Years Anniversary Symposium

• Thursday, September 26, 14.30
• CCBIO Lecture
• Helga Salvesen, Department of Gynecology of Obstetrics, Haukeland University Hospital, Bergen
• Individualized therapy based on molecular alterations in gynecologic cancer

• Thursday, October 3, 14.30
• Gaetano Finocchiaro, Unit of Molecular Neuro-Oncology, Neurological Institute C. Besta, Milan, Italy
• Immunotherapy of glioblastoma multiforme

• Thursday, October 10 - Cancelled
• Maximiliano Suster, Neural Circuits and Behaviour Group, Uni Research AS, Bergen

• Thursday, October 17, 14.30
• Tone Tønjum, Department of Microbiology, University of Oslo, Oslo University Hospital (Rikshospitalet)
• Novel biomarkers for preclinical Alzheimer's disease: Focus on DNA repair

• Thursday, October 24, 14.30
• Dominik N. Müller, Max Delbrück Center for Molecular Medicine and Experimental and Clinical Research Center, Berlin, Germany
• High salt (NaCl) affects Th17 polarization

• Thursday, October 31, 14.30
• CCBIO Lecture
• Oddbjørn Straume, Centre for Cancer Biomarkers (CCBIO), Department of Clinical Science, University of Bergen
• Angiogenic biomarkers in malignant melanoma

• Thursday, November 7, 14.30
• Daniela Elena Costea, Department of Biomedicine, University of Bergen
• Carcinoma-associated fibroblasts promote a cancer stem cell-like phenotype through TGFβ1 secretion

• Thursday, November 14, 14.30
• Gilbert Weidinger, Institute for Biochemistry and Molecular Biology, Ulm University, Germany
• Mechanisms of naturally occurring organ regeneration in the zebrafish

• Thursday, November 21, 14.30 - NB! Auditorium 2
• The Falch Lecture 2013
• Kari Alitalo, Wihuri Research Institute and Translational Cancer Biology Program, Biomedicum Helsinki, University of Helsinki, Finland
• Biological functions and therapeutic potential of endothelial growth factors 

• Thursday, November 28, 14.30
• CCBIO Lecture
• Bjørn Tore Gjertsen, Centre for Cancer Biomarkers (CCBIO), Department of Clinical Science, University of Bergen, and Department of Internal Medicine, Haukeland University Hospital
• Phosphoprotein signaling in acute myeloid leukemia

• Thursday, December 5, 14.30
• Paivi Kettunen, Department of Biomedicine, University of Bergen
• Molecular regulation of development of tooth innervation

• Thursday, December 12 - NB! 13.00
• Part of the Symposium in Memory of Hans-Hermann Gerdes
• Joachim P. Spatz, Department of New Materials and Biosystems, Max Planck Institute for Intelligent Systems, Stuttgart, and Department of Biophysical Chemistry, University of Heidelberg, Germany
• Cellular nanotubes guided by nanopattern biointerfaces

• Thursday, December 19 - Cancelled
• Anne K. Jonassen, Department of Biomedicine, University of Bergen

Spring 2012

• Thursday, January 19, 13.00
• Christian A. Vedeler, Department of Neurology, Haukeland University Hospital, Bergen
• Paraneoplastic neurological syndromes

• Thursday, January 26, 13.00
• Bryndis Birnir, Department of Neuroscience, Uppsala University, Sweden
• Insulin and GABA as mediators in cross-talks between the metabolic and the nervous systems

• Thursday, February 2, 13.00
• Marc Rehmsmeier, Computational Biology Unit (CBU), Uni Computing, Uni Research, University of Bergen
• It's not the size that matters but what you do with it. DNA sequence principles in the era of genome-wide datasets

• Thursday, February 9, 13.00
• Taija Makinen, Lymphatic Development Laboratory, Cancer Research UK London Research Institute, London, UK
• Morphogenesis of the lymphatic vascular system

• Thursday, February 16, 13.00
• Ayumu Tashiro, Kavli Institute for Systems Neuroscience and Centre for the Biology of Memory, Norwegian University of Science and Technology and St. Olavs Hospital, Trondheim
• Activity-dependent mechanisms in circuit formation through adult neurogenesis

• Thursday, February 23, 13.00
• Karsten Specht, Department of Biological and Medical Psychology, Bergen fMRI-Group, University of Bergen
• When a sound becomes a word
  Tracing the ventral stream for speech perception with functional imaging: a meta-analysis

• Thursday, March 1  - No seminar

• Thursday, March 8, 13.00
• Helga B. Salvesen, Department of Obstetrics and Gynecology, Haukeland University Hospital, Bergen
• New targets for personalised medicine in endometrial cancer

• Thursday, March 15, 13.00
• Kevin Knower, Cancer Drug Discovery Laboratory, Prince Henry's Institute of Medical Research, Clayton, VIC, Australia
• Epigenetic markers of oestrogen production in the breast

• Thursday, March 22, 13.00
• Thoralf Christoffersen, Department of Pharmacology, Institute of Clinical Medicine, University of Oslo
• The evasive target: Signal transduction and antitumour therapy

• Thursday, March 29, 13.00
• Aurélia E. Lewis, Department of Molecular Biology, University of Bergen
• Lipid signalling and function in the cell nucleus

• Thursday, April 12, 13.00
• Kamal Babikeir Eln Mustafa, Department of Clinical Dentistry, University of Bergen
• Stem cells and biomedical engineering

• Thursday, April 19, 13.00
• Suzanne J. Baker, Department of Developmental Neurobiology, St. Jude Children’s Research Hospital, Memphis, TN, USA
• Genomic alterations in pediatric high-grade glioma

• Thursday, April 26, 13.00
• Mathias Ziegler, Department of Molecular Biology, University of Bergen
• Generation and functions of subcellular NAD pools – key determinants of bioenergetic and signaling pathways

• Thursday, May 3, 13.00 - Seminar postponed until August 30
• Katherine A. Hajjar, Department of Cell and Developmental Biology, Weill Cornell Medical College, New York, NY, USA
• The annexin A2 system and angiogenesis: Lessons from the knockout mouse

• Thursday, May 10, 13.00
• Ellen Berggreen, Department of Biomedicine, University of Bergen
• Dental infectious diseases and the lymphatic system

• Thursday, May 24, 13.00
• Arturo Muga, Biophysics Unit and Department of Biochemistry and Molecular Biology, University of the Basque Country, Bilbao, Spain
• ClpB, a disaggregase machine

• NB! Friday, June 1, 13.00
• Kristen M. Harris, Center for Learning and Memory, Institute for Neuroscience, The University of Texas at Austin, TX, USA
• Structural synaptic scaling during long-term potentiation (LTP)

• Thursday, June 7, 13.00
• Marco Conti, Department of Gynecology, Obstetrics, and Reproductive Sciences, Center for Reproductive Sciences, University of California, San Francisco (UCSF), CA, USA
• Role of PDE4 in shaping the ß-adrenergic signals

• Thursday, June 14, 13.00
• Michael J. Berridge, Babraham Institute, Cambridge, UK
• Calcium signalling in health and disease

Autumn 2012

• Thursday, August 9, 13.00
• Juan A. Hermoso, Department of Crystallography and Structural Biology, Institute of Physical Chemistry “Rocasolano”, Spanish National Research Council (CSIC), Madrid, Spain
• Unraveling the host-pathogen interactions in Streptococcus pneumoniae by X-ray crystallography
   
• Thursday, August 16, 13.00
• Roger H. Adamson, Department of Physiology and Membrane Biology, University of California at Davis, CA, USA
• Regulation of microvascular permeability: an in vivo perspective

• Thursday, August 23, 13.00
• Ragna Sannerud, Laboratory of Membrane Trafficking, Center for Human Genetics, Catholic University of Leuven and VIB Center for the Biology of Disease, Leuven, Belgium
• Sorting out the cell biology of Alzheimer’s disease: Focus on BACE1 and APP

• Thursday, August 30, 13.00
• Katherine A. Hajjar, Department of Cell and Developmental Biology, Weill Cornell Medical College, New York, NY, USA
• The annexin A2 system and angiogenesis: Lessons from the knockout mouse

• Thursday, September 6, 13.00 - NB! Auditorium 2
• The Kavli Prize Symposium in Neuroscience (invited speaker)
• Michael E. Greenberg, Department of Neurobiology, Harvard Medical School, Boston MA, USA
• Neuronal activity-dependent signaling: Networks that regulate synapse development and cognitive function

• Thursday, September 13, 13.00
• René Westerhausen, Department of Biological and Medical Psychology, University of Bergen
• Cognitive control of auditory speech perception

• Thursday, September 20, 13.00
• Michael Z. Lin, Departments of Pediatrics and Bioengineering, Stanford University, CA, USA
• Teaching an old dog lots of new tricks: Extending fluorescent protein uses in neuroscience and stem cell biology

• Thursday, September 27, 13.00
• Gareth Griffiths, Department of Molecular Biosciences, University of Oslo
• Development of biodegradable nanoparticles enclosing antibiotics against Mycobacterium tuberculosis in macrophages and in a zebrafish model system

• Thursday, October 4, 13.00
• Heather A. Cameron, National Institute of Mental Health, National Institutes of Health, Bethesda, MD, USA
• Maturation and function of new neurons in the adult hippocampus

• Thursday, October 11  -  No seminar

• Thursday, October 18 - NB! 14.00
• Frank Winkler, Department of Neurooncology, Neurology Clinic and National Center for Tumor Disease, University Hospital Heidelberg, Germany
• Seeing is believing is understanding: Intravital microscopy of brain tumor progression and response to therapy

• Thursday, October 25, 13.00 - NB! Auditorium 2
• The 5th NorMIC Symposium (invited speaker)
• Ben N. G. Giepmans, Department of Cell Biology, University Medical Center Groningen, University of Groningen, The Netherlands
• Fluorescence microscopy meets electron microscopy

• Thursday, November 1 - Seminar postponed to 2013
• The Falch Lecture 2012
• Kari Alitalo, Molecular/Cancer Biology Laboratory, Biomedicum Helsinki, University of Helsinki, Finland

• Thursday, November 8, 13.00
• Rainer Pepperkok, Cell Biology and Biophysics Unit, European Molecular Biology Laboratory (EMBL), Heidelberg, Germany
• High throughput microscopy to study membrane traffic and disease mechanisms

• Thursday, November 15, 13.00
• Jason Matthews, Department of Pharmacology and Toxicology, University of Toronto, ON, Canada
• New mechanisms of AHR function using zinc finger nuclease-mediated gene knockout and identification of TiPARP (ARTD14) as a repressor of AHR transactivation

• Thursday, November 22, 13.00
• Lena Claesson-Welsh, Department of Immunology, Genetics and Pathology, Uppsala University, Sweden
• Histidine-rich glycoprotein in tumor vessel normalization and anti-tumor immune responsiveness

• Thursday, November 29, 13.00
• Biokjemisk Kollokvium (NBS, Bergen Division)
• Gregor Anderluh, Laboratory for Molecular Biology and Nanobiotechnology, National Institute of Chemistry, Ljubljana, and Infrastructural Centre for Molecular Interactions Analysis, Department of Biology, University of Ljubljana, Slovenia
• Perforin adventures on lipid membranes

• Thursday, December 6, 13.00
• Andrea Trentani, Department of Neurodegeneration Research, Neurology & GI Centre of Excellence for Drug Discovery, GlaxoSmithKline Pharmaceuticals, Harlow, UK
• Regulation of hippocampal neurogenesis in healthy aging and Alzheimer’s disease

• Thursday, December 13, 13.00
• The Nansen Neuroscience Network Symposium (invited speaker)
• Janne Sande Mathisen, Smartfish AS, Oslo Innovation Center
• Medical food for the clinical dietary management of brain disorders

• NB! Wednesday, December 19, 13.00
• Werner J. H. Koopman, Department of Biochemistry, Nijmegen Centre  for Molecular Life Sciences (NCMLS), Radboud University Medical Centre, Nijmegen, The Netherlands
• Cellular pathophysiology and therapy of mitochondrial OXPHOS disorders

Spring 2011

• Thursday, Jan. 13, 13:00
• Heidi Erlandsen, Institute of Oral Health Research, University of Alabama at Birmingham, AL, USA
• Structural and biophysical characterization of enamel matrix proteins

• Thursday, Jan. 20 - no BBB Seminar

• Thursday, Jan. 27, 13.00
• Ole A. Andreassen, Division of Mental Health and Addiction, Oslo University Hospital and Institute of Clinical Medicine, University of Oslo  
• Breakthrough in schizophrenia genetics – implications for disease mechanisms? 

• Thursday, Febr. 3, 13.00 - no BBB Seminar

• Thursday, Febr. 10, 13.00 - Cancelled
• Simon Geir Møller, Centre for Organelle Research, University of Stavanger
• Fe-S cluster biogenesis, oxidative stress and Parkinson’s Disease: Merging plants, zebrafish and humans

• Thursday, Febr. 17, 13.00
• Sjoukje Kuipers, Department of Biomedicine, University of Bergen
• From neurogenesis to synaptic plasticity: ARChing the gap

• Thursday, Febr. 24, 13.00
• Christian Sorg, Department of Psychiatry, Neuroradiology and Nuclear Medicine, Munich Technical University, Germany
• Affective disorders and the default mode and salience network

• Thursday, March 3, 13.00
• Kenneth Hugdahl, Department of Biological and Medical Psychology, University of Bergen, and Division of Psychiatry, Haukeland University Hospital
• Brain markers of auditory hallucinations in schizophrenia

• Thursday, March 10, 13.00
• Biokjemisk Kollokvium (NBS, Bergen Division)
• Alex Bateman, Wellcome Trust Sanger Institute, Wellcome Trust Genome Campus, Hinxton, UK
• Why biologists should care about Wikipedia

• Thursday, March 17, 13.00
• Anna Aragay, Molecular Biology Institute of Barcelona (IBMB), Spanish Research Council (CSIC), Spain, and Department of Biomedicine, University of Bergen
• New paradigms for G-proteins (mitochondria) and chemokine signaling

• Thursday, March 24, 13.00 - Cancelled
• Svante Pääbo, Max Planck Institute for Evolutionary Anthropology, Leipzig, Germany

• Thursday, March 31, 13.00
• Dominique Lombardo, French National Institute of Health and Medical Research (INSERM), Marseille, France
• Immunotherapy of pancreatic cancer

• Thursday, April 7, 13.00
• Graça Raposo-Benedetti, Structure and Membrane Compartments, National Center for Scientific  Research (CNRS), Institut Curie, Paris, France 
• Endosome dynamics in the biogenesis of lysosome-related organelles

• Thursday, April 14, 13.00
• Nobel Laureate in Physiology or Medicine 2008
• Harald zur Hausen, German Cancer Research Center (DKFZ), Heidelberg, Germany
• Infections in human cancer - results and perspectives

• Thursday, April 28, 13.00
• Pierre-Hervé Luppi, Center of Neuroscience of Lyon, National Center for Scientific Research (CNRS), Claude Bernard University Lyon, France
• The neuronal network responsible for paradoxical (REM) sleep and its dysfunctions causing narcolepsy and REM behavior disorder

• Thursday, May 5, 13.00
• Bjarte Håvik, Department of Clinical Medicine, Section of Medical Genetics and Molecular Medicine, Haukeland University Hospital, Bergen
• The effect of synaptic activity-regulated genes on the risk of schizophrenia

• Thursday, May 12, 13.00
• Arranged in cooperation with the research group Oral infections and inflammations at the Department of Clinical Dentistry and the Bergen Research School in Inflammation (BRSI)
• Sandra Kleinau, Department of Cell and Molecular Biology, Biomedical Center, Uppsala University, Sweden  
• Regulation of B lymphocytes and autoimmunity 

• Thursday, May 19, 13.00
• Peter Gunning, Oncology Research Unit, Department of Pharmacology, School of Medical Sciences, University of New South Wales, Sydney, Australia
• BioArchitecture, the actin cytoskeleton and a new therapeutic opportunity

• Thursday, May 26, 13.00 - Cancelled
• Nicolai Miosge, Tissue Regeneration Group, Department of Prosthodontics, Georg-August-University Göttingen, Germany
• Migratory progenitor cells in osteoarthritis and rheumatoid arthritis are driven by inflammatory mediators and sex hormones

• Thursday, June 9, 13:00
• Biokjemisk Kollokvium (NBS, Bergen Division)
• David A. Case, Department of Chemistry & Chemical Biology and BioMaPS Institute, Rutgers University, Piscataway, NJ, USA
• Biomolecular simulations: implicit solvent models and protein-ligand interactions

• Thursday, June 16, 13.00
• Björn Dahlbäck, Department of Laboratory Medicine, Lund University, Skåne University Hospital, Malmö, Sweden
• Gas6 and the TAM tyrosine kinase receptor family in apoptotic cell  clearance, autoimmunity and renal cell carcinoma

Autumn 2011

• Thursday, August 25, 13:00
• Olav Tenstad, Department of Biomedicine, University of Bergen
• Molecular imaging of single kidney function using a novel PET-probe

• Thursday, September 1, 13.00 
• Anders Tengholm, Department of Medical Cell Biology, Uppsala University, Sweden
• Dynamic imaging of plasma membrane signaling underlying insulin secretion

• Thursday, September 8, 13.00
• Georg Ebers, Wellcome Trust Centre for Human Genetics and Department of Clinical Neurology, John Radcliffe Hospital, University of Oxford, UK
• The cause of multiple sclerosis

• Thursday, September 15, 13.00
• Anatoliy A. Gashev, Department of Systems Biology and Translational Medicine, College of Medicine, Texas A&M Health Science Center, Temple, TX, USA
• Mechanisms of lymph transport and their aging

• Thursday, September 22, 13.00 - No seminar

• Thursday, September 29,  NB! Two seminars
• 11.00, Auditorium 2
• Kathryn J. Jeffery, Institute of Behavioural Neuroscience, Department of Cognitive, Perceptual and Brain Sciences, University College London, UK
• Navigating in a 3D world – is the brain's map of space actually flat?
• 13.00, Auditorium 4
• Jonathan P. Sleeman, Center for Biomedicine and Medical Technology Mannheim (CBTM), University of Heidelberg, and Karlsruhe Institute of Technology (KIT), Germany
• The contribution of the lymphatic system to metastatic spread

• Thursday, October 6, 13.00
• Rein Aasland, Department of Molecular Biology, University of Bergen
• The CW domain: a novel histone recognition module in chromatin regulators

• Thursday, October 13, NB! 14.30, Auditorium 2
• Dietmar Georg, Division of Medical Radiation Physics, Department of Radiotherapy, Medical University of Vienna/AKH Wien, Austria
• Flattening filter free photon beams - a new standard for advanced photon beam therapy techniques?

• Thursday, October 20, 13.00
• Elina Ikonen, Institute of Biomedicine, University of Helsinki, Finland
• Cholesterol-regulated signaling and transport in endo-lysosomes

• Thursday, October 27, 13.00
• Minoru Ueda, Department of Oral and Maxillofacial Surgery, Nagoya University, School of Medicine, Japan
• Brain and spinal code regeneration using dental pulp stem cells and their derived factors

• Thursday, November 3, 13.00
• Janne Grønli, Department of Biological and Medical Psychology, University of Bergen, and
  Norwegian Competence Center for Sleep Disorders, Haukeland University Hospital, Bergen
• Lifetime consequences of maternal separation – behaviour, sleep, circadian rhythms and brain activity

• Thursday, November 10, 13.00
• Igor N. Berezovsky, Computational Biology Unit, Uni Research, University of Bergen
• Protein stability, function and evolution

• Thursday, November 17, 13.00
• James C. Mulloy, Division of Experimental Hematology and Cancer Biology, Cincinnati Children's Hospital Medical Center, OH, USA
• Mouse models of acute leukemia: Oncogene-expressing human stem cells in the immunocompromised mouse

• Thursday, November 24, 13.00
• Frank Nilsen, Sea Lice Research Centre and Department of Biology, University of Bergen
• Host parasite interactions between the salmon louse and Atlantic salmon revealed by transcriptomic analysis

• Thursday, December 1, 13.00
• Michaela Kuhn, Institute of Physiology, University of Würzburg, Germany
• Endothelial actions of natriuretic peptides

• Thursday, December 8, 13.00 - Cancelled
• Gary F. Baxter, Division of Pharmacology, Welsh School of Pharmacy, Cardiff University, UK

• NB! Friday, December 16, 13.00
• Gunter Meister, Department of Biochemistry I, University of Regensburg, Germany
• Mechanisms of microRNA-guided gene silencing

Spring 2010

• Thursday, Jan. 14, 13:00
• Johanna Myllyharju, Oulu Center for Cell-Matrix Research, Biocenter Oulu and Department of Medical Biochemistry and Molecular Biology, University of Oulu, Finland
• 4-Hydroxyprolines, from collagens to the regulation of oxygen homeostasis and beyond

• Thursday, Jan. 21, 13:00
• Boris Lenhard, Computational Biology Unit, Bergen Center for Computational Science and Sars Centre for Marine Molecular Biology, University of Bergen
• Disease susceptibility variants mapping within long-range regulatory domains of transcription factor genes

• Thursday, Jan. 28, 13:00
• Biokjemisk Kollokvium (NBS, Bergen Division)
• Gunnar von Heijne, Center for Biomembrane Research, Department of Biochemistry and Biophysics, Stockholm University, Sweden
• Insertion of membrane proteins into the endoplasmic reticulum

• Thursday, Febr. 04, 13:00
• Laurence Bindoff, Department of Clinical Medicine, University of Bergen
• Studying mitochondrial disease mechanisms

• Thursday, Febr. 11, 13:00
• Joel Glover, Department of Physiology, Institute of Basic Medical Sciences, University of Oslo; Norwegian Center for Stem Cell Research, Oslo University Hospital and Sars International Centre for Marine Molecular Biology, Bergen
• Optical recording of the functional development of neuronal circuits

• Thursday, Febr. 18, 13:00
• Karl-Henning Kalland, The Gade Institute, University of Bergen
• Genome-wide analysis of coordinated gene expression in a cell culture model of stepwise EMT and malignant transformation

• Thursday, Febr. 25, 13:00
• Frits Thorsen, Molecular Imaging Centre (MIC), Department of Biomedicine, University of Bergen
• MR imaging of malignant brain tumour models in small rodents 

• Thursday, March 11, 13:00
• Martha Chekenya, Department of Biomedicine, University of Bergen
• Preclinical validation of targeting NG2/MPG as a therapy for human brain tumours

• Thursday, March 18, 13:00
• Börje Haraldsson, Nephrology, Institute of Medicine, Sahlgrenska Academy and University Hospital, Gothenburg, Sweden
• Mechanism behind proteinuria; is there a role for the glomerular endothelium?

• Thursday, March 25, 13:00
• Lars-Gunnar Larsson, Department of Microbiology, Tumor and Cell Biology (MTC), Karolinska Institutet, Stockholm, Sweden
• Regulation of cellular senescence by the Myc oncoprotein

• Thursday, April 8, 13:00
• Andrew Leask, Division of Oral Biology, Schulich School of Medicine and Dentistry, University of Western Ontario, London, ON, Canada
• Scar wars: Signaling networks causing fibrosis

• Thursday, April 15, 13:00
• Richard Alan Engh, The Norwegian Structural Biology Centre, Department of Chemistry, University of Tromsø
• Rationalizing protein kinase inhibitor selectivity profiles

• Thursday, April 22, 13:00 -  Cancelled!
• Patrik Brundin, Neuronal Survival Unit, Wallenberg Neuroscience Center, Department of Experimental Medical Science, Lund University, Sweden
• Is Parkinson’s disease a “prion-like” disorder? 

• Thursday, April 29, 13:00  
• Elizabeth S. Sztul, Department of Cell Biology, University of Alabama, Birmingham, USA
• Molecular regulation of membrane traffic

• Thursday, May 6, 13:00   
• Keshav K. Singh, Department of Cancer Genetics, Roswell Park Cancer Institute, Buffalo, NY, USA
• Intergenomic cross talk and its role in tumorigenesis

• Thursday, May 20, 13:00   
• Patric K. Stanton, Department of Cell Biology and Anatomy, New York Medical College, Valhalla, NY, USA
• Visualization of long-term plasticity of vesicular transmitter release using two-photon laser scanning microscopy

• Thursday, May 27, 13:00    
• Neil A. Hanley, Endocrinology & Diabetes, School of Biomedicine, Manchester Academic Health Science Centre, University of Manchester, UK
• Human endocrine development; focus on adrenal and pancreas

• Thursday, June 3, 13:00
• Øyvind Halskau, Department of Biomedicine, University of Bergen
• Interplay of non-native, dynamic and flexible protein states in protein-protein and protein-membrane interactions

• Thursday, June 10, 13:00   
• Andreas Reif, Department of Psychiatry, Psychosomatics and Psychotherapy, University of Würzburg, Germany
• Nitric oxide synthase-I (NOS-I) and brain function

Autumn 2010

• Thursday, Aug. 26, 13:00
• Antonella Viola, Laboratory of Adaptive Immunity, Department of Translational Medicine, University of Milan, I.R.C.C.S. Istituto Clinico Humanitas, Milan, Italy
• Costimulation at the immunological synapse

• Thursday, Sept. 2, 13:00 - no BBB Seminar

• Thursday, Sept. 9, 13:00
• Jens Titze, Department of Nephrology and Hypertension, Friedrich-Alexander
  University, Erlangen-Nürnberg, Germany
• Extrarenal regulation of volume and blood pressure homeostasis

• Thursday, Sept. 16, 13:00
• Andreas Hejnol, Sars International Centre for Marine Molecular Biology, Bergen
• From genomes to morphology – the role of development in the evolution of complexity 

• Thursday, Sept. 23, 13:00
• Michael Coleman, Laboratory of Molecular Signaling, The Babraham Institute, Cambridge, UK
• Regulation of axon degeneration in injury and disease by delivery of Nmnat enzymes

• Thursday, Sept. 30, 13:00
• Jean Gruenberg, Department of Biochemistry, University of Geneva, Switzerland
• Multivesicular endosome biogenesis and signaling

• Thursday, Oct. 7, 13:00
• Arne Östman, Department of Oncology-Pathology, Karolinska Institutet, Stockholm, Sweden
• The molecular basis of the effects of cancer-associated fibroblasts on tumor progression and response to therapy

• Thursday, Oct. 14, 13:00 - no BBB seminar (autumn holidays)

• Thursday, Oct. 21, 13:00
• Emmet McCormack, Section for Haematology, Institute of Medicine, University of Bergen
• Co-inhibition of MDM2 and HDAC synergistically activate p53 mediated apoptosis in acute myeloid leukemia

• Thursday, Oct. 28, 13:00
• Attila Aszodi, Department of Molecular Medicine, Max Planck Institute of Biochemistry, Martinsried, Germany
• The role of β1 integrins in skeletal development: lessons from knockout mice
   
• Thursday, Nov.  4, 13:00
• Biokjemisk Kollokvium (NBS, Bergen Division)
• Harald Stenmark, Centre for Cancer Biomedicine, University of Oslo
• A lipid kinase in membrane dynamics and tumour suppression

• Thursday, Nov.  11, 13:00
• Biokjemisk Kollokvium (NBS, Bergen Division)
• Mark von Zastrow, Department of Psychiatry, Department of Cellular and Molecular Pharmacology, and Program in Cell Biology, UCSF School of Medicine, San Francisco, CA, USA
• Regulation of neural signaling receptors by membrane traffic in the endocytic pathway

• Thursday, Nov.  18, 13:00
• Michael Leitges, The Biotechnology Centre of Oslo, University of Oslo
• Roles of individual Protein Kinase C isoforms during tumorigenesis

• Thursday, Nov.  25, 13:00 - Cancelled

• Thursday, Dec.  2, 13:00 - Postponed to 24.02.2011
• Christian Sorg, Department of Psychiatry, University Hospital rechts der Isar, Munich Technical University, Germany
• Affective disorders and the default mode and salience network

• Thursday,  Dec. 9, 13:00
• Piergiorgio Percipalle, Department of Cell and Molecular Biology, Karolinska Institutet, Stockholm, Sweden
• Actin and actin-associated proteins in transcriptional and post-transcriptional control of gene expression

• Thursday,  Dec. 16, 13:00
• Boris Hinz, Laboratory of Tissue Repair and Regeneration, Matrix Dynamics Group, University of Toronto, ON, Canada
• Myofibroblasts and the matrix
   

Spring 2009

• Thursday, Jan. 22, 13.00
• Jaakko Saraste, Department of Biomedicine, University of Bergen
• Mapping novel transport routes to the cell surface

• Thursday, Jan. 29, 13.00
• Helge Wiig, Department of Biomedicine, University of Bergen
• Access to the tissue microenvironment through isolation of interstitial fluid and lymph

• Thursday, Febr. 5, 13.00
• Alexandre Micoulet, Department of Biomedicine, University of Bergen
• Nano- and micro-systems to study cell mechanics and adhesion

• Thursday, Febr. 12, 13.00 - Postponed to April 16th, due to Darwin 200 arrangement
• Rebecca J. Cox Brokstad, Influenza Center, The Gade Institute, University of Bergen
• Influenza pandemics and development of pandemic influenza vaccines

• Thursday, Febr. 19, 13.00
• Nathalie Reuter, Computational Biology Unit, BCCS, University of Bergen
• A structural perspective on the original functions of human proteinase 3; On the predictive power of structural computational biology

• Thursday, Febr. 26, 13.00
• Clive R. Bramham, Department of Biomedicine and Bergen Mental Health Research Center,  University of Bergen
• The Arc of synaptic memory

• Thursday, March 5, Cancelled!
• Fatima H. Labeed, Centre for Biomedical Engineering, School of Engineering, University of Surrey, Guildford, UK
• Dielectrophoresis: a non-invasive electrophysiological tool for cellular analysis

• Tuesday, March 17, 13.00 NB! Day
• Biokjemisk Kollokvium (NBS, Bergen Division):
  John Mattick, Institute for Molecular Bioscience, University of Queensland, Brisbane, Australia
• The hidden layer of RNA regulation in the evolution, development and cognition of complex organisms

• Thursday, March 19, 13.00
• Thomas Deller, Department of Clinical Neuroanatomy, Goethe-University of Frankfurt, Frankfurt am Main, Germany
• Dendritic remodelling after axonal denervation

• Thursday, March 26, 13.00
• Hee-Chan Seo, Department of Molecular Biology, University of Bergen
• Transcription factors in zebrafish development – contributions from duplicated genes

• Thursday, April 2, 13.00
• Fabian Rentzsch, Sars International Centre for Marine Molecular Biology, Bergen
• Early steps in nervous system evolution: neural development in a sea anemone

• Thursday, April 16, 13.00
• Rebecca J. Cox Brokstad, Influenza Center, The Gade Institute, University of Bergen
• Influenza pandemics and development of pandemic influenza vaccines

• Thursday, April 23, 13.00
• Carol MacKintosh, MRC Protein Phosphorylation Unit, College of Life Sciences, University of Dundee, UK
• The digital logic of 14-3-3 proteins in growth factor and insulin signaling

• Thursday, April 30, 13.00
• Clive D'Santos, PROBE Proteomics Platform, Department of Biomedicine, University of Bergen
• Mass spectrometry-based proteomics in the biological sciences 

• Thursday, May 7, 13.00
• Astrid Gräslund, Department of Biochemistry and Biophysics, Arrhenius Laboratories, Stockholm University, Sweden
• The amyloid β-peptide involved in Alzheimer´s disease: molecular interactions and secondary structure conversions

• Thursday, May 14, 13.00
• Margareta Müller, German Cancer Research Center (DKFZ), Heidelberg, Germany
• It takes two to tango: The tumor and its stroma

• Thursday, May 28, 13.00
• Amanda Swain, Section of Gene Function and Regulation, Institute of Cancer Research, London, UK
• Transcriptional regulation of early gonad and adrenal development

• Thursday, June 4, 13.00
• Ammon B. Peck, Department of Pathology, Immunology and Laboratory Medicine, University of Florida, Gainesville, FL, USA
• Identification of candidate genes and signaling pathways in autoimmunity using genomic microarrays

• Thursday, June 11, 13.00
• Carol A. Barnes, Departments of Psychology, Neurology and Biology and Evelyn F. McKnight Brain Institute, University of Arizona, Tucson, AZ, USA
• Neural correlates of memory change in normal aging

Autumn 2009

• Thursday, Aug. 20, 13:00
• Thomas Arnesen, Department of Molecular Biology and Department of Surgical Sciences, University of Bergen
• Protein N-terminal acetylation - From basic principles to human medicine

• Thursday, Aug. 27, 13.00
• David Schaffer, Berkeley Stem Cell Center & The Helen Wills Neuroscience Institute, University of California, Berkeley, CA, USA
• Molecular elucidation and engineering of stem cell microenvironment

• Thursday, Sept. 3, 13.00
  Arvid Lundervold, Neuroinformatics and Image Analysis Laboratory & Molecular Imaging Center, Department of Biomedicine, University of Bergen & Department of Radiology, Haukeland University Hospital
• Biomedical image analysis - challenges, solutions and local organization

• Thursday, Sept. 10, 13.00 
• Frode S. Berven, Proteomics Unit in Bergen (PROBE), Department of Biomedicine, University of Bergen
• Biomarker discovery in multiple sclerosis patients
   
• Thursday, Sept. 17, 13.00
• Torgeir Flatmark, Department of Biomedicine, University of Bergen
• Glucokinase - the key enzyme in the regulated exocytotic release of insulin from pancreatic beta-cells
   
• Thursday, Sept. 24, 13.00
• Inger Sandlie, Department of Molecular Biosciences, University of Oslo
• Engineering the recognition molecules of the adaptive immune system
   
• Thursday, Oct. 1, 13.00
• David Micklem, Department of Biomedicine, University of Bergen, and BerGenBio AS, Bergen
• Functional genetic discovery of an essential role for Axl in breast cancer metastasis
   
• Thursday, Oct. 8, 13.00
• Matthias Chiquet, Department of Anatomy, University of Bern, Switzerland
• Unraveling a RhoA-dependent mechanotransduction pathway in fibroblasts
   
• Thursday, Oct. 15, 13.00
• Thomas Seufferlein, Department of Internal Medicine I, University Clinic and Polyclinic for Internal Medicine, Martin-Luther University Halle-Wittenberg, Halle (Saale), Germany
• Regulation of tumor angiogenesis by protein kinase D2
   
• Thursday, Oct. 22, 13.00
• Daniela Elena Costea, Section for Pathology, The Gade Institute, University of Bergen
• Epithelial-mesenchymal interactions in human oral mucosa:
  Studies on in vitro 3D models
   
• Thursday, Oct. 29, 13.00
• Biokjemisk Kollokvium (NBS, Bergen Division)
• Peter Parker, Protein Phosphorylation Laboratory, London Research Institute, Cancer Research UK, London, UK
• Mapping, monitoring and meddling in PKC action
   
• Thursday, Nov. 5, 13.00
• Ole Skøtt, Institute of Medical Biology, University of Southern Denmark, Odense, Denmark
• Proteinuria and sodium retention: a novel mechanism

• Thursday, Nov. 12, 13.00 - Cancelled!
• Biokjemisk Kollokvium (NBS, Bergen Division)
• Harald Stenmark, Centre for Cancer Biomedicine, University of Oslo
   
• Thursday, Nov. 19, 13.00
• Lena Kjellén, Department of Medical Biochemistry and Microbiology, Uppsala University, Sweden, and Department of Biomedicine, University of Bergen
• Mast cell development: role of enzymes involved in heparin biosynthesis
   
• Thursday, Nov. 26, 13.00 
• Beate Eckes, Department of Dermatology, University of Cologne, Germany.
• Crucial role for integrin-linked kinase in fibroblast functions
   
• Thursday, Dec. 3, 13.00
• Johanna Ivaska, Medical Biotechnology, VTT Technical Research Centre of Finland, and Centre for Biotechnology, University of Turku, Finland
• Regulation of epithelial cell migration, invasion and EMT
   
• Thursday, Dec. 10, 13.00
• Marion Kusche-Gullberg, Department of Biomedicine, University of Bergen
• EXT-dependent regulation of fibroblast-matrix interactions and cell signaling
   
• Thursday, Dec. 17, 13.00 - Cancelled!
• Frits Thorsen, Molecular Imaging Centre (MIC), Department of Biomedicine, University of Bergen
• MR imaging of malignant brain tumour models in small rodents